Click a Venn or table area to retrieve the receptors with the given Arrestin family profile.
Class:
| Class (Family) |
A (Rhodopsin) | B1 (Secretin) | B2 (Adhesion) | C (Glutamate) | F (Frizzled) | T2 (Taste 2) | Total |
| Beta-Arrestin-1 | 63 | 9 | 0 | 0 | 0 | 0 | 72 |
| Beta-Arrestin-2 | 73 | 9 | 0 | 1 | 0 | 0 | 83 |
| Total (unique) | 73 | 9 | 0 | 1 | 0 | 0 | 83 |
| Class | Ligand type | Receptor Family | Receptor (UniProt) |
Receptor (GtP) |
|---|---|---|---|---|
The four dots depict Arrestin coupling.
Receptor names:
Class A
(Rhodopsin)
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Class A
Orphans
Class B1
(Secretin)
Class B2
(Adhesion)
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Class C
(Glutamate)
Class F
(Frizzled)
Class T
(Taste 2)
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References
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet, C., Mancini, A., Breton, B., Le Gouill, C., Hauser, A.S., Normand, C., Kobayashi, H., Gross, F., Hogue, M., Lukasheva, V., St-Onge, S., Carrier, M., Héroux, M., Morissette, S., Fauman, E.B., Fortin, J.P., Schann, S., Leroy, X., Gloriam, D.E., Bouvier, M.
eLife. 2022 doi: 10.7554/eLife.74101