The four dots depict Arrestin coupling.


Receptor names:

Arrestin complexes
⬤ β-Arrestin1 ⬤ β-Arrestin2 ⬤ Arrestin-C ⬤ S-Arrestin

Class A
(Rhodopsin)




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)

References

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet, C., Mancini, A., Breton, B., Le Gouill, C., Hauser, A.S., Normand, C., Kobayashi, H., Gross, F., Hogue, M., Lukasheva, V., St-Onge, S., Carrier, M., Héroux, M., Morissette, S., Fauman, E.B., Fortin, J.P., Schann, S., Leroy, X., Gloriam, D.E., Bouvier, M.
eLife. 2022 doi: 10.7554/eLife.74101