ArrestinDb

Beta-arrestin-1 - SST2 receptor complex model

Full

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

ARRESTIN FAMILY

Beta

DATE

2025-02-19

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.

Tertiary structure confidence

Chain	pLDDT score avg
SST2	75.1
Beta-arrestin-1	81.7

Very high (>90)

Confident (90-70)

Low (70-50)

Very low (<50)

Disordered

PTM Score: 0.7

iPTM Score: 0.6

PAE mean: 15.7

GPCR - Arrestin interface interactions

The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (arrestin residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.

Interaction definitions:

Residue numbering:

GPCR-Arrestin backbone (bb) or sidechain (sc):

bb-bb

bb-sc

sc-sc

sc-bb

Structures

Sequence Color

Arrestin, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Search:

Interaction type	GPCR Segment	AA	Number	Generic number	Arrestin segment	AA	Number	Generic number

Interaction type	GPCR Segment	AA	Number	Generic number	Arrestin segment	AA	Number	Generic number

Hydrophobic	TM3	V	144	3x54	S6	F	75	N.S6.01
Hydrophobic	TM6	R	247	6x26	S6	F	75	N.S6.01
Hydrophobic	H8	K	321	8x52	s20c	E	405	C.s20c.15
Hydrophobic	TM2	T	78	2x39	s5s6	D	67	N.s5s6.04
Hydrophobic	TM3	V	144	3x54	s5s6	L	73	N.s5s6.10
Hydrophobic	ICL2	K	149	34x52	s15s16	T	246	C.s15s16.05
Hydrophobic	TM2	T	76	2x37	s8s9	T	136	N.s8s9.07
Hydrophobic	TM4	R	155	4x38	s17s18	R	285	C.s17s18.11
Hydrophobic	ICL3	V	242	-	s15s16	F	244	C.s15s16.03
Hydrophobic	ICL2	K	149	34x52	S16	A	247	C.S16.01
Hydrophobic	TM5	I	231	5x61	s5s6	L	71	N.s5s6.08
Hydrophobic	ICL2	I	148	34x51	s15s16	N	245	C.s15s16.04
Hydrophobic	TM6	M	257	6x36	s5s6	L	71	N.s5s6.08
Hydrophobic	TM5	V	235	5x65	S6	F	75	N.S6.01
Hydrophobic	H8	N	318	8x49	s5s6	D	69	N.s5s6.06
Hydrophobic	TM3	A	143	3x53	s5s6	L	68	N.s5s6.05
Hydrophobic	ICL2	I	148	34x51	S15	I	241	C.S15.14
Hydrophobic	TM3	V	144	3x54	s5s6	L	71	N.s5s6.08
Hydrophobic	ICL2	R	154	34x57	s5s6	D	67	N.s5s6.04
Hydrophobic	TM5	V	235	5x65	s5s6	L	73	N.s5s6.10
Hydrophobic	TM6	M	257	6x36	s5s6	V	70	N.s5s6.07
Hydrophobic	TM3	R	140	3x50	s5s6	L	71	N.s5s6.08
Hydrophobic	TM6	K	253	6x32	s5s6	G	72	N.s5s6.09
Hydrophobic	ICL1	K	75	12x51	s8s9	T	136	N.s8s9.07
Hydrophobic	ICL2	I	148	34x51	S16	Y	249	C.S16.03
Hydrophobic	H8	D	317	8x48	s5s6	D	69	N.s5s6.06
Hydrophobic	ICL2	I	148	34x51	S5	Y	63	N.S5.12
Hydrophobic	TM4	P	156	4x39	s8s9	E	134	N.s8s9.05
Hydrophobic	ICL3	V	242	-	S6	R	76	N.S6.02
Hydrophobic	TM3	V	144	3x54	s5s6	L	68	N.s5s6.05
Hydrophobic	ICL2	K	152	34x55	S16	Y	249	C.S16.03
Hydrophobic	ICL2	I	148	34x51	S16	A	247	C.S16.01
Hydrophobic	ICL2	P	147	34x50	S5	Y	63	N.S5.12
Hydrophobic	ICL2	I	148	34x51	S9	C	140	N.S9.01
Hydrophobic	TM3	H	146	3x56	s15s16	N	245	C.s15s16.04
Hydrophobic	TM6	V	258	6x37	s5s6	L	71	N.s5s6.08
Hydrophobic	ICL2	P	147	34x50	s15s16	N	245	C.s15s16.04
Hydrophobic	TM6	V	254	6x33	s5s6	L	71	N.s5s6.08
Hydrophobic	TM6	V	254	6x33	s5s6	L	73	N.s5s6.10
Hydrophobic	TM2	T	78	2x39	s5s6	V	70	N.s5s6.07
Hydrophobic	H8	S	316	8x47	s5s6	V	70	N.s5s6.07
Hydrophobic	TM2	I	82	2x43	s5s6	V	70	N.s5s6.07
Hydrophobic	ICL3	V	242	-	S6	K	77	N.S6.03
Hydrophobic	ICL2	A	151	34x54	s5s6	R	65	N.s5s6.02
Hydrophobic	TM3	R	140	3x50	s5s6	V	70	N.s5s6.07
Hydrophobic	TM6	R	247	6x26	s15s16	F	244	C.s15s16.03
Hydrophobic	TM5	S	238	5x68	s15s16	F	244	C.s15s16.03
Ionic	ICL1	K	73	12x49	s20c	D	402	C.s20c.12
Ionic	H8	K	321	8x52	s20c	E	405	C.s20c.15
Ionic	ICL2	R	154	34x57	s5s6	D	67	N.s5s6.04
Ionic	ICL1	K	75	12x51	s20c	D	402	C.s20c.12
Ionic	H8	K	321	8x52	s20c	E	407	C.s20c.17
Ionic	ICL3	R	241	-	s17s18	E	313	C.s17s18.39
Polar	ICL1	K	73	12x49	s20c	D	402	C.s20c.12
Polar	H8	K	321	8x52	s20c	E	405	C.s20c.15
Polar	TM2	T	78	2x39	s5s6	D	67	N.s5s6.04
Polar	ICL2	K	149	34x52	s15s16	T	246	C.s15s16.05
Polar	H8	S	316	8x47	s5s6	D	69	N.s5s6.06
Polar	H8	N	318	8x49	s5s6	E	66	N.s5s6.03
Polar	ICL2	R	154	34x57	s5s6	R	65	N.s5s6.02
Polar	TM6	S	250	6x29	s5s6	G	72	N.s5s6.09
Polar	H8	N	318	8x49	s5s6	D	69	N.s5s6.06
Polar	ICL2	R	154	34x57	s5s6	D	67	N.s5s6.04
Polar	ICL2	I	148	34x51	S16	Y	249	C.S16.03
Polar	ICL1	K	75	12x51	s20c	D	402	C.s20c.12
Polar	H8	D	317	8x48	s5s6	D	69	N.s5s6.06
Polar	H8	K	321	8x52	s20c	E	407	C.s20c.17
Polar	ICL2	P	147	34x50	S5	Y	63	N.S5.12
Polar	TM3	H	146	3x56	s15s16	N	245	C.s15s16.04
Polar	TM5	K	234	5x64	s15s16	F	244	C.s15s16.03
Polar	ICL3	R	241	-	S6	K	77	N.S6.03
Polar	TM6	S	244	6x23	S6	D	78	N.S6.04
Polar	ICL3	R	241	-	s17s18	E	313	C.s17s18.39
Polar	ICL2	A	151	34x54	s5s6	R	65	N.s5s6.02
Polar	TM3	R	140	3x50	s5s6	V	70	N.s5s6.07
Van-der-waals	TM6	R	247	6x26	S6	F	75	N.S6.01
Van-der-waals	ICL1	K	73	12x49	s20c	D	402	C.s20c.12
Van-der-waals	H8	K	321	8x52	s20c	E	405	C.s20c.15
Van-der-waals	TM2	T	78	2x39	s5s6	D	67	N.s5s6.04
Van-der-waals	TM3	V	144	3x54	s5s6	L	73	N.s5s6.10
Van-der-waals	ICL2	K	149	34x52	s15s16	T	246	C.s15s16.05
Van-der-waals	H8	S	316	8x47	s5s6	D	69	N.s5s6.06
Van-der-waals	ICL3	V	242	-	s15s16	F	244	C.s15s16.03
Van-der-waals	TM6	M	257	6x36	s5s6	L	71	N.s5s6.08
Van-der-waals	ICL2	R	154	34x57	s5s6	R	65	N.s5s6.02
Van-der-waals	H8	N	318	8x49	s5s6	D	69	N.s5s6.06
Van-der-waals	TM3	A	143	3x53	s5s6	L	68	N.s5s6.05
Van-der-waals	ICL2	I	148	34x51	S15	I	241	C.S15.14
Van-der-waals	TM3	V	144	3x54	s5s6	L	71	N.s5s6.08
Van-der-waals	ICL2	R	154	34x57	s5s6	D	67	N.s5s6.04
Van-der-waals	TM6	M	257	6x36	s5s6	V	70	N.s5s6.07
Van-der-waals	ICL2	I	148	34x51	S16	Y	249	C.S16.03
Van-der-waals	H8	D	317	8x48	s5s6	D	69	N.s5s6.06
Van-der-waals	ICL2	I	148	34x51	S5	Y	63	N.S5.12
Van-der-waals	ICL3	V	242	-	S6	R	76	N.S6.02
Van-der-waals	TM3	V	144	3x54	s5s6	L	68	N.s5s6.05
Van-der-waals	H8	K	321	8x52	s20c	E	407	C.s20c.17
Van-der-waals	ICL2	I	148	34x51	S16	A	247	C.S16.01
Van-der-waals	ICL2	P	147	34x50	S5	Y	63	N.S5.12
Van-der-waals	TM3	H	146	3x56	s15s16	N	245	C.s15s16.04
Van-der-waals	ICL2	P	147	34x50	s15s16	N	245	C.s15s16.04
Van-der-waals	TM6	V	254	6x33	s5s6	L	71	N.s5s6.08
Van-der-waals	TM6	V	254	6x33	s5s6	L	73	N.s5s6.10
Van-der-waals	TM5	K	234	5x64	s15s16	F	244	C.s15s16.03
Van-der-waals	ICL3	R	241	-	S6	K	77	N.S6.03
Van-der-waals	TM2	T	78	2x39	s5s6	V	70	N.s5s6.07
Van-der-waals	ICL3	R	241	-	s17s18	E	313	C.s17s18.39
Van-der-waals	ICL2	A	151	34x54	s5s6	R	65	N.s5s6.02
Van-der-waals	TM3	R	140	3x50	s5s6	V	70	N.s5s6.07
Van-der-waals	TM6	R	247	6x26	s15s16	F	244	C.s15s16.03
Van-der-waals	TM5	S	238	5x68	s15s16	F	244	C.s15s16.03

Showing 1 to 111 of 111 entries

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Main reference

Beta-arrestin-1 - SST2 receptor complex model Download Full