ArrestinDb

Beta-arrestin-1 - SST3 receptor complex model

Full

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

ARRESTIN FAMILY

Beta

DATE

2025-02-19

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.

Tertiary structure confidence

Chain	pLDDT score avg
SST3	66.6
Beta-arrestin-1	80.9

Very high (>90)

Confident (90-70)

Low (70-50)

Very low (<50)

Disordered

PTM Score: 0.6

iPTM Score: 0.6

PAE mean: 16.7

GPCR - Arrestin interface interactions

The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (arrestin residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.

Interaction definitions:

Residue numbering:

GPCR-Arrestin backbone (bb) or sidechain (sc):

bb-bb

bb-sc

sc-sc

sc-bb

Structures

Sequence Color

Arrestin, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Search:

Interaction type	GPCR Segment	AA	Number	Generic number	Arrestin segment	AA	Number	Generic number

Interaction type	GPCR Segment	AA	Number	Generic number	Arrestin segment	AA	Number	Generic number

Aromatic	TM5	K	232	5x64	s15s16	F	244	C.s15s16.03
Hydrophobic	TM3	R	141	3x50	s5s6	V	70	N.s5s6.07
Hydrophobic	H8	R	319	8x49	s20c	E	404	C.s20c.14
Hydrophobic	ICL2	R	155	34x57	s5s6	D	67	N.s5s6.04
Hydrophobic	TM5	V	233	5x65	s5s6	L	73	N.s5s6.10
Hydrophobic	TM5	A	236	5x68	s15s16	F	244	C.s15s16.03
Hydrophobic	TM5	V	233	5x65	S6	F	75	N.S6.01
Hydrophobic	C-term	E	350	-	s20c	R	418	C.s20c.28
Hydrophobic	ICL2	T	149	34x51	S16	A	247	C.S16.01
Hydrophobic	TM2	T	79	2x39	s5s6	V	70	N.s5s6.07
Hydrophobic	ICL2	P	148	34x50	s15s16	N	245	C.s15s16.04
Hydrophobic	TM3	A	144	3x53	s5s6	D	67	N.s5s6.04
Hydrophobic	TM3	V	145	3x54	s15s16	F	244	C.s15s16.03
Hydrophobic	ICL3	A	242	-	S6	D	78	N.S6.04
Hydrophobic	H8	R	326	8x56	s20c	E	407	C.s20c.17
Hydrophobic	H8	Y	318	8x48	s5s6	D	69	N.s5s6.06
Hydrophobic	TM3	V	145	3x54	s5s6	L	73	N.s5s6.10
Hydrophobic	TM6	M	258	6x36	s5s6	V	70	N.s5s6.07
Hydrophobic	H8	R	319	8x49	s5s6	E	66	N.s5s6.03
Hydrophobic	TM3	V	145	3x54	S6	F	75	N.S6.01
Hydrophobic	TM3	V	145	3x54	s5s6	L	68	N.s5s6.05
Hydrophobic	H8	S	317	8x47	s5s6	D	69	N.s5s6.06
Hydrophobic	ICL2	A	152	34x54	s5s6	R	65	N.s5s6.02
Hydrophobic	TM3	V	145	3x54	s5s6	L	71	N.s5s6.08
Hydrophobic	TM2	I	83	2x43	s5s6	V	70	N.s5s6.07
Hydrophobic	ICL2	P	148	34x50	S5	Y	63	N.S5.12
Hydrophobic	TM3	A	144	3x53	s5s6	L	68	N.s5s6.05
Hydrophobic	ICL2	T	149	34x51	S5	Y	63	N.S5.12
Hydrophobic	ICL2	P	148	34x50	s15s16	F	244	C.s15s16.03
Hydrophobic	TM6	R	254	6x32	s5s6	G	72	N.s5s6.09
Hydrophobic	TM5	I	229	5x61	s5s6	L	71	N.s5s6.08
Hydrophobic	TM5	K	232	5x64	s15s16	F	244	C.s15s16.03
Hydrophobic	TM5	V	240	5x72	S6	K	77	N.S6.03
Hydrophobic	TM6	V	255	6x33	s5s6	L	73	N.s5s6.10
Hydrophobic	ICL2	T	149	34x51	S15	I	241	C.S15.14
Hydrophobic	TM6	M	258	6x36	s5s6	L	71	N.s5s6.08
Hydrophobic	ICL3	S	244	-	S6	D	78	N.S6.04
Hydrophobic	ICL3	A	242	-	S6	K	77	N.S6.03
Hydrophobic	ICL2	T	149	34x51	S16	Y	249	C.S16.03
Hydrophobic	H8	S	317	8x47	s5s6	V	70	N.s5s6.07
Hydrophobic	TM5	V	240	5x72	S6	R	76	N.S6.02
Hydrophobic	H8	R	319	8x49	s5s6	D	69	N.s5s6.06
Hydrophobic	TM3	R	141	3x50	s5s6	L	71	N.s5s6.08
Hydrophobic	TM5	Y	226	5x58	s5s6	L	71	N.s5s6.08
Ionic	H8	R	319	8x49	s20c	E	404	C.s20c.14
Ionic	ICL2	R	155	34x57	s5s6	D	67	N.s5s6.04
Ionic	C-term	E	350	-	s20c	R	418	C.s20c.28
Ionic	TM5	R	239	5x71	s17s18	E	313	C.s17s18.39
Ionic	H8	R	326	8x56	s20c	E	407	C.s20c.17
Ionic	H8	R	319	8x49	s5s6	E	66	N.s5s6.03
Polar	TM3	R	141	3x50	s5s6	V	70	N.s5s6.07
Polar	H8	R	319	8x49	s20c	E	404	C.s20c.14
Polar	ICL2	R	155	34x57	s5s6	D	67	N.s5s6.04
Polar	C-term	E	350	-	s20c	R	418	C.s20c.28
Polar	TM5	R	239	5x71	s17s18	E	313	C.s17s18.39
Polar	H8	R	326	8x56	s20c	E	407	C.s20c.17
Polar	H8	Y	318	8x48	s5s6	D	69	N.s5s6.06
Polar	TM5	R	239	5x71	S6	K	77	N.S6.03
Polar	H8	R	319	8x49	s5s6	E	66	N.s5s6.03
Polar	H8	Q	322	8x52	s20c	E	407	C.s20c.17
Polar	ICL2	P	148	34x50	s5s6	R	65	N.s5s6.02
Polar	ICL1	S	75	12x50	s8s9	T	136	N.s8s9.07
Polar	H8	S	317	8x47	s5s6	D	69	N.s5s6.06
Polar	ICL2	T	149	34x51	s15s16	N	245	C.s15s16.04
Polar	TM6	R	254	6x32	s5s6	G	72	N.s5s6.09
Polar	TM4	A	157	4x39	s8s9	E	134	N.s8s9.05
Polar	TM5	K	232	5x64	s15s16	F	244	C.s15s16.03
Polar	TM5	K	232	5x64	s15s16	N	245	C.s15s16.04
Polar	H8	R	319	8x49	s8s9	T	136	N.s8s9.07
Polar	ICL3	S	244	-	S6	D	78	N.S6.04
Polar	H8	R	319	8x49	s5s6	D	69	N.s5s6.06
Van-der-waals	TM3	R	141	3x50	s5s6	V	70	N.s5s6.07
Van-der-waals	H8	R	319	8x49	s20c	E	404	C.s20c.14
Van-der-waals	ICL2	R	155	34x57	s5s6	D	67	N.s5s6.04
Van-der-waals	TM5	V	233	5x65	s5s6	L	73	N.s5s6.10
Van-der-waals	TM5	A	236	5x68	s15s16	F	244	C.s15s16.03
Van-der-waals	TM5	V	233	5x65	S6	F	75	N.S6.01
Van-der-waals	C-term	E	350	-	s20c	R	418	C.s20c.28
Van-der-waals	ICL2	T	149	34x51	S16	A	247	C.S16.01
Van-der-waals	TM2	T	79	2x39	s5s6	V	70	N.s5s6.07
Van-der-waals	ICL2	P	148	34x50	s15s16	N	245	C.s15s16.04
Van-der-waals	TM5	R	239	5x71	s17s18	E	313	C.s17s18.39
Van-der-waals	TM3	V	145	3x54	s15s16	F	244	C.s15s16.03
Van-der-waals	ICL3	A	242	-	S6	D	78	N.S6.04
Van-der-waals	H8	R	326	8x56	s20c	E	407	C.s20c.17
Van-der-waals	H8	Y	318	8x48	s5s6	D	69	N.s5s6.06
Van-der-waals	TM5	R	239	5x71	S6	K	77	N.S6.03
Van-der-waals	TM6	M	258	6x36	s5s6	V	70	N.s5s6.07
Van-der-waals	H8	R	319	8x49	s5s6	E	66	N.s5s6.03
Van-der-waals	TM3	V	145	3x54	s5s6	L	68	N.s5s6.05
Van-der-waals	H8	Q	322	8x52	s20c	E	407	C.s20c.17
Van-der-waals	ICL2	P	148	34x50	s5s6	R	65	N.s5s6.02
Van-der-waals	ICL2	A	152	34x54	s5s6	R	65	N.s5s6.02
Van-der-waals	TM3	V	145	3x54	s5s6	L	71	N.s5s6.08
Van-der-waals	ICL2	P	148	34x50	S5	Y	63	N.S5.12
Van-der-waals	ICL2	T	149	34x51	S5	Y	63	N.S5.12
Van-der-waals	ICL2	T	149	34x51	s15s16	N	245	C.s15s16.04
Van-der-waals	TM5	K	232	5x64	s15s16	F	244	C.s15s16.03
Van-der-waals	TM5	K	232	5x64	s15s16	N	245	C.s15s16.04
Van-der-waals	TM5	V	240	5x72	S6	K	77	N.S6.03
Van-der-waals	TM6	V	255	6x33	s5s6	L	73	N.s5s6.10
Van-der-waals	TM3	V	146	3x55	s15s16	N	245	C.s15s16.04
Van-der-waals	TM6	M	258	6x36	s5s6	L	71	N.s5s6.08
Van-der-waals	ICL3	S	244	-	S6	D	78	N.S6.04
Van-der-waals	ICL2	T	149	34x51	S16	Y	249	C.S16.03
Van-der-waals	H8	R	319	8x49	s5s6	D	69	N.s5s6.06

Showing 1 to 106 of 106 entries

Join us

Cite us

Main reference

Beta-arrestin-1 - SST3 receptor complex model Download Full