ArrestinDb

Beta-arrestin-1 - TAS2R20 complex model

Full

GPCR CLASS (FAMILY)

T2 (Taste 2)

SPECIES

Homo sapiens

ARRESTIN FAMILY

Beta

DATE

2025-02-19

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.

Tertiary structure confidence

Chain	pLDDT score avg
TAS2R20	80.8
Beta-arrestin-1	79.5

Very high (>90)

Confident (90-70)

Low (70-50)

Very low (<50)

Disordered

PTM Score: 0.6

iPTM Score: 0.4

PAE mean: 21.1

GPCR - Arrestin interface interactions

The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (arrestin residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.

Interaction definitions:

Residue numbering:

GPCR-Arrestin backbone (bb) or sidechain (sc):

bb-bb

bb-sc

sc-sc

sc-bb

Structures

Sequence Color

Arrestin, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Search:

Interaction type	GPCR Segment	AA	Number	Generic number	Arrestin segment	AA	Number	Generic number

Interaction type	GPCR Segment	AA	Number	Generic number	Arrestin segment	AA	Number	Generic number

Aromatic	TM5	H	205	5x68	s15s16	F	244	C.s15s16.03
Aromatic	TM5	H	205	5x68	S6	F	75	N.S6.01
Aromatic	TM6	H	224	6x31	S6	F	75	N.S6.01
Hydrophobic	TM6	V	231	6x38	s5s6	L	71	N.s5s6.08
Hydrophobic	TM7	G	282	7x56	s5s6	L	71	N.s5s6.08
Hydrophobic	TM6	I	223	6x30	s5s6	T	74	N.s5s6.11
Hydrophobic	H8	K	284	8x48	s20c	E	407	C.s20c.17
Hydrophobic	H8	K	284	8x48	s5s6	G	72	N.s5s6.09
Hydrophobic	TM5	H	205	5x68	s15s16	F	244	C.s15s16.03
Hydrophobic	TM3	K	109	3x53	s5s6	D	67	N.s5s6.04
Hydrophobic	ICL2	R	123	34x55	s8s9	T	136	N.s8s9.07
Hydrophobic	TM5	M	209	5x72	s15s16	L	243	C.s15s16.02
Hydrophobic	TM6	H	224	6x31	s15s16	F	244	C.s15s16.03
Hydrophobic	TM6	T	230	6x37	s5s6	L	71	N.s5s6.08
Hydrophobic	TM5	H	205	5x68	S6	F	75	N.S6.01
Hydrophobic	TM1	R	38	1x64	s20c	E	405	C.s20c.15
Hydrophobic	TM3	Y	106	3x50	s5s6	V	70	N.s5s6.07
Hydrophobic	ICL2	N	112	34x44	s15s16	N	245	C.s15s16.04
Hydrophobic	TM5	H	212	5x75	s17s18	E	313	C.s17s18.39
Hydrophobic	ICL2	N	112	34x44	s5s6	R	65	N.s5s6.02
Hydrophobic	TM3	F	105	3x49	s5s6	V	70	N.s5s6.07
Hydrophobic	TM6	H	224	6x31	s5s6	L	73	N.s5s6.10
Hydrophobic	TM3	Y	106	3x50	s5s6	L	71	N.s5s6.08
Hydrophobic	TM5	M	209	5x72	S6	K	77	N.S6.03
Hydrophobic	TM5	L	198	5x61	s5s6	L	71	N.s5s6.08
Hydrophobic	TM3	I	110	3x54	s5s6	V	70	N.s5s6.07
Hydrophobic	TM6	S	220	6x27	S6	R	76	N.S6.02
Hydrophobic	TM3	K	109	3x53	s8s9	K	138	N.s8s9.09
Hydrophobic	TM5	M	209	5x72	s15s16	F	244	C.s15s16.03
Hydrophobic	TM2	A	44	2x39	s5s6	V	70	N.s5s6.07
Hydrophobic	TM6	S	220	6x27	S6	F	75	N.S6.01
Hydrophobic	ICL2	K	122	34x54	s8s9	T	136	N.s8s9.07
Hydrophobic	TM6	A	227	6x34	s5s6	L	71	N.s5s6.08
Hydrophobic	TM3	I	110	3x54	s5s6	R	65	N.s5s6.02
Hydrophobic	TM5	M	209	5x72	S6	F	75	N.S6.01
Hydrophobic	TM3	I	110	3x54	s5s6	D	67	N.s5s6.04
Hydrophobic	TM6	A	227	6x34	s5s6	L	73	N.s5s6.10
Hydrophobic	TM6	H	224	6x31	S6	F	75	N.S6.01
Hydrophobic	TM3	I	110	3x54	s5s6	L	71	N.s5s6.08
Hydrophobic	TM5	K	208	5x71	s17s18	E	313	C.s17s18.39
Hydrophobic	TM6	I	223	6x30	s5s6	L	73	N.s5s6.10
Hydrophobic	TM3	I	110	3x54	s5s6	L	73	N.s5s6.10
Hydrophobic	TM7	G	282	7x56	s5s6	G	72	N.s5s6.09
Ionic	H8	K	284	8x48	s20c	E	407	C.s20c.17
Ionic	TM3	K	109	3x53	s5s6	D	67	N.s5s6.04
Ionic	TM3	K	109	3x53	s5s6	E	66	N.s5s6.03
Ionic	TM1	R	38	1x64	s20c	E	405	C.s20c.15
Ionic	TM5	H	212	5x75	s17s18	E	313	C.s17s18.39
Ionic	ICL2	K	122	34x54	s5s6	D	67	N.s5s6.04
Ionic	TM5	K	208	5x71	s17s18	E	313	C.s17s18.39
Polar	H8	Q	288	8x52	s20c	E	407	C.s20c.17
Polar	H8	K	284	8x48	s20c	E	407	C.s20c.17
Polar	TM3	K	109	3x53	s5s6	R	65	N.s5s6.02
Polar	TM5	H	205	5x68	s15s16	F	244	C.s15s16.03
Polar	TM3	K	109	3x53	s5s6	D	67	N.s5s6.04
Polar	TM3	K	109	3x53	s5s6	E	66	N.s5s6.03
Polar	TM1	R	38	1x64	s20c	E	405	C.s20c.15
Polar	TM3	Y	106	3x50	s5s6	V	70	N.s5s6.07
Polar	ICL2	N	112	34x44	s15s16	N	245	C.s15s16.04
Polar	TM5	H	212	5x75	s17s18	E	313	C.s17s18.39
Polar	ICL2	N	112	34x44	s5s6	R	65	N.s5s6.02
Polar	TM6	S	220	6x27	S6	R	76	N.S6.02
Polar	TM3	I	110	3x54	s5s6	R	65	N.s5s6.02
Polar	TM5	K	208	5x71	s17s18	E	313	C.s17s18.39
Polar	TM7	G	282	7x56	s5s6	G	72	N.s5s6.09
Van-der-waals	TM6	V	231	6x38	s5s6	L	71	N.s5s6.08
Van-der-waals	TM7	G	282	7x56	s5s6	L	71	N.s5s6.08
Van-der-waals	TM6	I	223	6x30	s5s6	T	74	N.s5s6.11
Van-der-waals	H8	K	284	8x48	s20c	E	407	C.s20c.17
Van-der-waals	TM5	H	205	5x68	s15s16	F	244	C.s15s16.03
Van-der-waals	TM3	K	109	3x53	s5s6	D	67	N.s5s6.04
Van-der-waals	ICL2	R	123	34x55	s8s9	T	136	N.s8s9.07
Van-der-waals	TM6	H	224	6x31	s15s16	F	244	C.s15s16.03
Van-der-waals	TM6	T	230	6x37	s5s6	L	71	N.s5s6.08
Van-der-waals	TM5	H	205	5x68	S6	F	75	N.S6.01
Van-der-waals	TM1	R	38	1x64	s20c	E	405	C.s20c.15
Van-der-waals	TM3	Y	106	3x50	s5s6	V	70	N.s5s6.07
Van-der-waals	ICL2	N	112	34x44	s15s16	N	245	C.s15s16.04
Van-der-waals	TM5	H	212	5x75	s17s18	E	313	C.s17s18.39
Van-der-waals	ICL2	N	112	34x44	s5s6	R	65	N.s5s6.02
Van-der-waals	TM3	Y	106	3x50	s5s6	L	71	N.s5s6.08
Van-der-waals	TM6	S	220	6x27	S6	R	76	N.S6.02
Van-der-waals	TM2	A	44	2x39	s5s6	V	70	N.s5s6.07
Van-der-waals	TM6	S	220	6x27	S6	F	75	N.S6.01
Van-der-waals	ICL2	K	122	34x54	s8s9	T	136	N.s8s9.07
Van-der-waals	TM3	I	110	3x54	s5s6	R	65	N.s5s6.02
Van-der-waals	TM3	I	110	3x54	s5s6	D	67	N.s5s6.04
Van-der-waals	TM6	A	227	6x34	s5s6	L	73	N.s5s6.10
Van-der-waals	TM6	H	224	6x31	S6	F	75	N.S6.01
Van-der-waals	TM3	I	110	3x54	s5s6	L	71	N.s5s6.08
Van-der-waals	TM5	K	208	5x71	s17s18	E	313	C.s17s18.39
Van-der-waals	TM6	I	223	6x30	s5s6	L	73	N.s5s6.10
Van-der-waals	TM7	G	282	7x56	s5s6	G	72	N.s5s6.09

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Beta-arrestin-1 - TAS2R20 complex model Download Full