Structure information

GABAB1

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

7C7Q

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

A

REFERENCE

10.1038/S41422-020-0350-5

PUBLICATION DATE

July 1, 2020

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
(-)-baclofen W182 N-term aromatic (face-to-edge)
(-)-baclofen S247 N-term polar (hydrogen bond)
(-)-baclofen S247 N-term polar (hydrogen bond with backbone)
(-)-baclofen S247 N-term polar (hydrogen bond)
(-)-baclofen G268 N-term Van der Waals
(-)-baclofen S270 N-term polar (hydrogen bond)
(-)-baclofen S270 N-term Van der Waals
(-)-baclofen H287 N-term polar (hydrogen bond)
(-)-baclofen F319 N-term Van der Waals
(-)-baclofen F319 N-term hydrophobic
(-)-baclofen F366 N-term Van der Waals
(-)-baclofen Y367 N-term polar (hydrogen bond)
(-)-baclofen Y367 N-term aromatic (edge-to-face)
(-)-baclofen I393 N-term Van der Waals
(-)-baclofen I393 N-term hydrophobic
(-)-baclofen W395 N-term hydrophobic
(-)-baclofen W395 N-term Van der Waals
(-)-baclofen Y396 N-term Van der Waals
(-)-baclofen E466 N-term polar (charge-assisted hydrogen bond)
rac-BHFF A788 5.58x58 TM5 hydrophobic
rac-BHFF Y789 5.59x59 TM5 aromatic (edge-to-face)
rac-BHFF K792 5.62x62 TM5 polar (charge-assisted hydrogen bond)
rac-BHFF G806 6.40x40 TM6 Van der Waals
rac-BHFF M807 6.41x41 TM6 Van der Waals
rac-BHFF Y810 6.44x44 TM6 Van der Waals
rac-BHFF Y810 6.44x44 TM6 hydrophobic

Ligands

(-)-baclofen

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


rac-BHFF

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

V A L V I G L S S L V S V S I F L K 1 N L T A V G C S L A L A A V F P L G L 2 T F M S G Y G L S F G L G L L W L R A Q 3 L Y A T V G L L V G M D V L T L A I W Q 4 A L F I G L L L L L G K Y G Y F I G L W 5 G M A I Y N V A V L C L I T A P V T M I 6 V L T I Y S S F V I A L S A F A F A A 7
Download: PNG | SVG
ICL1 V S H R Y I Q N S ICL1ECL1 D G Y H I G R N ECL1ICL2 T K K E E K K E W R K T L ICL2ECL2 P L H R T I E T F A K E E P K E D I D V S I L P Q L E H C S S R ECL2ICL3 S V S T E K I N ICL3ECL3 S S Q Q D ECL3N-term M L L L L L L A P L F L R P P G A G G A Q T P N A T S E G C Q I I H P P W E G G I R Y R G L T R D Q V K A I N F L P V D Y E I E Y V C R G E R E V V G P K V R K C L A N G S W T D M D T P S R C V R I C S K S Y L T L E N G K V F L T G G D L P A L D G A R V D F R C D P D F H L V G S S R S I C S Q G Q W S T P K P H C Q V N R T P H S E R R A V Y I G A L F P M S G G W P G G Q A C Q P A V E M A L E D V N S R R D I L P D Y E L K L I H H D S K C D P G Q A T K Y L Y E L L Y N D P I K I I L M P G C S S V S T L V A E A A R M W N L I V L S Y G S S S P A L S N R Q R F P T F F R T H P S A T L H N P T R V K L F E K W G W K K I A T I Q Q T T E V F T S T L D D L E E R V K E A G I E I T F R Q S F F S D P A V P V K N L K R Q D A R I I V G L F Y E T E A R K V F C E V Y K E R L F G K K Y V W F L I G W Y A D N W F K I Y D P S I N C T V D E M T E A V E G H I T T E I V M L N P A N T R S I S N M T S Q E F V E K L T K R L K R H P E E T G G F Q E A P L A Y D A I W A L A L A L N K T S G G G G R S G V R L E D F N Y N N Q T I T D Q I Y R A M N S S S F E G V S G H V V F D A S G S R M A W T L I E Q L Q G G S Y K K I G Y Y D S T K D D L S W S K T D K W I G G S P P A D Q T L V I K T F R F L S Q N-termC-term T G S S T N N N E E E K S R L L E K E N R E L E K I I A E K E E R V S E L R H Q L Q S R Q Q L R S R R H P P T P P E P S G G L P R G P P E P P D R L S C D G S R V H L L Y K C-term K L F I S V S V L S S L G I V L A V V C L S F N I Y N Q P N L N N L T A V G C S L A L A A V F P L G L Q F P F V C Q A R L W L L G L G F S L G Y G S M F T K I W W V H T V F E P W K L Y A T V G L L V G M D V L T L A I W Q I V D K M N T W L G I F Y G Y K G L L L L L G I F L A Y E T K D H R A V G M A I Y N V A V L C L I T A P V T M I L A A F A F A S L A I V F S S Y I T L V V L F V P K M R R L I T R G E W Q D T Q S E A M K
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(C)
GABAB1
TM5
5x58 5.58x58 A788
5x59 5.59x59 Y789
5x62 5.62x62 K792
TM6
6x38 6.40x40 G806
6x39 6.41x41 M807
6x42 6.44x44 Y810