Structure information

GPBA receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7CFN

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Sept. 9, 2020

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
S-EMCA L71 2.60x60 TM2 hydrophobic
S-EMCA L74 2.63x63 TM2 hydrophobic
S-EMCA F96 3.36x36 TM3 hydrophobic
S-EMCA L105 3.45x45 TM3 hydrophobic
S-EMCA L130 4.48x48 TM4 Van der Waals
S-EMCA L130 4.48x48 TM4 polar (hydrogen bond with backbone)
S-EMCA T131 4.49x49 TM4 Van der Waals
S-EMCA T131 4.49x49 TM4 polar (hydrogen bond)
S-EMCA F161 ECL2 hydrophobic
S-EMCA L166 5.39x40 TM5 hydrophobic
S-EMCA Y240 6.51x51 TM6 polar (hydrogen bond)
S-EMCA Y240 6.51x51 TM6 Van der Waals
S-EMCA L244 6.55x55 TM6 hydrophobic
S-EMCA L244 6.55x55 TM6 Van der Waals
S-EMCA S247 6.58x58 TM6 polar (hydrogen bond)
S-EMCA S247 6.58x58 TM6 Van der Waals
S-EMCA Y251 6.62x62 TM6 hydrophobic
S-EMCA L266 7.39x38 TM7 Van der Waals

Ligands

S-EMCA

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Residue Diagrams

L N A T I I L S A L A L S L G L A G K P 1 L S L L L A G L L T G L A L P T L P G L 2 L L L N A L L S L F S F N P A L Y V L L 3 I R L A L L L T W A G P L L F A S L P A 4 S L F A A A G V A P L L L G Y V E L Y L Y 5 A G A M L L F G L C W G P Y V A T L L L 6 V P V A A A S A S G L S L L S L L T G 7
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ICL1 R R L R ICL1ECL1 W N Q S R R ECL1ICL2 P L Q P P G ICL2ECL2 W N H W T P G A N C S S Q A I F ECL2ICL3 R D E P ICL3ECL3 R P P L ECL3N-term M T P N S T G E V P S P I N-termC-term R C L Q G L W G R A S R D S P G P S I A Y H P S S Q S S V D L D L N C-term P K G A L G L S L A L A S L I I T A N L L L A L G I A W D S P P A G C F F L S L L L A G L L T G L A L P T L P G L G Y W S C L L V Y L A P N F S F L S L L A N L L L V H G E R Y M A V L R S I R L A L L L T W A G P L L F A S L P A L G P A P Y L Y L E V Y G L L L P A V G A A A F L S V R V L A T A H R Q L Q D I C R L E R A V C S A L A R A L T W R Q A R A Q A G A M L L F G L C W G P Y V A T L L L S V L A Y E Q G P G T L L S L L S L G S A S A A A V P V A M G L G D Q R W R A Y T A P A A Q
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Residue Table


GPCRdb(A)
GPCRdb(A)
GPBA receptor
TM2
2x60 2.60x60 L71
2x63 2.63x63 L74
TM3
3x36 3.36x36 F96
3x45 3.45x45 L105
TM4
4x48 4.48x48 L130
4x49 4.49x49 T131
TM5
5x40 5.39x40 L166
TM6
6x51 6.51x51 Y240
6x55 6.55x55 L244
6x58 6.58x58 S247
6x62 6.62x62 Y251
TM7
7x38 7.39x38 L266