Structure information

mGlu2 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

7EPB

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-021-03641-W

PUBLICATION DATE

June 23, 2021

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Nanobody DN13 P46 N-term hydrophobic
Nanobody DN13 A47 N-term hydrophobic
Nanobody DN13 E48 N-term polar (charge-assisted hydrogen bond)
Nanobody DN13 G51 N-term Van der Waals
Nanobody DN13 P52 N-term Van der Waals
eglumegad R57 N-term polar (charge-assisted hydrogen bond)
eglumegad R61 N-term polar (charge-assisted hydrogen bond)
eglumegad S143 N-term polar (hydrogen bond with backbone)
eglumegad S143 N-term Van der Waals
eglumegad Y144 N-term hydrophobic
eglumegad Y144 N-term Van der Waals
eglumegad S145 N-term polar (hydrogen bond)
eglumegad S145 N-term polar (hydrogen bond with backbone)
eglumegad S145 N-term polar (hydrogen bond)
eglumegad A166 N-term Van der Waals
eglumegad A166 N-term polar (hydrogen bond with backbone)
eglumegad S167 N-term Van der Waals
eglumegad T168 N-term Van der Waals
eglumegad T168 N-term polar (hydrogen bond with backbone)
eglumegad Y216 N-term Van der Waals
eglumegad Y216 N-term hydrophobic
Nanobody DN13 E239 N-term polar (charge-assisted hydrogen bond)
Nanobody DN13 K240 N-term Van der Waals
Nanobody DN13 K240 N-term polar (hydrogen bond with backbone)
Nanobody DN13 V241 N-term Van der Waals
Nanobody DN13 V241 N-term polar (hydrogen bond with backbone)
Nanobody DN13 G242 N-term Van der Waals
Nanobody DN13 A244 N-term Van der Waals
Nanobody DN13 A244 N-term polar (hydrogen bond with backbone)
Nanobody DN13 M245 N-term polar (hydrogen bond with backbone)
Nanobody DN13 M245 N-term Van der Waals
Nanobody DN13 S246 N-term polar (hydrogen bond)
Nanobody DN13 R247 N-term Van der Waals
Nanobody DN13 R247 N-term polar (hydrogen bond with backbone)
Nanobody DN13 A248 N-term hydrophobic
Nanobody DN13 A248 N-term Van der Waals
Nanobody DN13 A249 N-term hydrophobic
Nanobody DN13 A249 N-term Van der Waals
Nanobody DN13 V253 N-term Van der Waals
Nanobody DN13 V253 N-term hydrophobic
eglumegad D295 N-term polar (charge-assisted hydrogen bond)
eglumegad K377 N-term polar (charge-assisted hydrogen bond)

Ligands

Nanobody DN13

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


eglumegad

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

L T A L A G L C A I T V P G V A W A D G 1 Y I L L G G V F L C Y C M T F I F I A 2 T L L A S Y C V S F A T G L G L R R L T 3 Q V A I C L A L I S G Q L L I V V A W L 4 A Y L T C L A I L L V N Y A L S G L M S 5 G F T M Y T T C I I W L A F L P I F Y V 6 G L V V S G S L S V S V C M T T T Q V R 7
Download: PNG | SVG
ICL1 T N A P V V K A S ICL1ECL1 K P ECL1ICL2 A R E G A Q R P R F I ICL2ECL2 A P G T G K E T A P E R R E V V T L R C N H R ECL2ICL3 P E N ICL3ECL3 S ECL3N-term M G S L L A L L A L L L L W G A V A E G P A K K V L T L E G D L V L G G L F P V H Q K G G P A E D C G P V N E H R G I Q R L E A M L F A L D R I N R D P H L L P G V R L G A H I L D S C S K D T H A L E Q A L D F V R A S L S R G A D G S R H I C P D G S Y A T H G D A P T A I T G V I G G S Y S D V S I Q V A N L L R L F Q I P Q I S Y A S T S A K L S D K S R Y D Y F A R T V P P D F F Q A K A M A E I L R F F N W T Y V S T V A S E G D Y G E T G I E A F E L E A R A R N I C V A T S E K V G R A M S R A A F E G V V R A L L Q K P S A R V A V L F T R S E D A R E L L A A S Q R L N A S F T W V A S D G W G A L E S V V A G S E G A A E G A I T I E L A S Y P I S D F A S Y F Q S L D P W N N S R N P W F R E F W E Q R F R C S F R Q R D C A A H S L R A V P F E Q E S K I M F V V N A V Y A M A H A L H N M H R A L C P N T T R L C D A M R P V N G R R L Y K D F V L N V K F D A P F R P A D T H N E V R F D R F G D G I G R Y N I F T Y L R A G S G R Y R Y Q K V G Y W A E G L T L D T S L I P W A S P S A G P L P A S R C S E P C L Q N E V K S V Q P G E V C C W L C I P C Q P Y E Y R L D E F T C A D C G L G Y W P N A S L T G C F E L P Q E Y I R W N-termC-term S R F G S A A A R A S S S L G Q G S G S Q F V P T V C N G R E V V D S T T S S L C-term G D A W A V G P V T I A C L G A L A T L F V L G V F V R H G R E L C Y I L L G G V F L C Y C M T F I F I A S T A V C T L R R L G L G T A F S V C Y S A L L T K T N R I A R I F G G S P A S Q V A I C L A L I S G Q L L I V V A W L V V E D A S M L G S L A Y N V L L I A L C T L Y A F K T R K C F N E A K F I G F T M Y T T C I I W L A F L P I F Y V T S D Y R V Q T T T M C V S V S L S G S V V L G C L F A P K L H I I L F Q P Q K H R A N V V S P T
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu2 receptor