Structure information

CX3CR1

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7XBW

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

R

REFERENCE

10.1126/SCIADV.ABN8048

PUBLICATION DATE

July 13, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Cholesterol L75 2.48x48 TM2 hydrophobic
Cholesterol L79 2.52x52 TM2 hydrophobic
Cholesterol L151 4.47x47 TM4 hydrophobic
Cholesterol W154 4.50x50 TM4 hydrophobic
Cholesterol I158 4.54x54 TM4 hydrophobic

Ligands

Cholesterol

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Residue Diagrams

L N G V L G I A F I V S Y F I S L F V T 1 L N L A L S D L L F V A T L P F W T H Y 2 V T I F F I S G F F G I F F F A T T F K 3 G V T I S L G V W A A A I L V A A P Q 4 Y C Y S M I L L P L L F G L F N T E V N R 5 L L V V I V F F L F W T P Y N V M I F L 6 L P N L C C H S F A V T E T V S L A L 7
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ICL1 K K P K ICL1ECL1 E K G L H N A ECL1ICL2 A A N S M N N R ICL2ECL2 K Q K E N E C L G D Y P E V ECL2ICL3 K N ICL3ECL3 F F P ECL3N-term M D Q F P E S V T E N F E Y D D L A E A C Y N-termC-term C L A V L C G R S V H V D F S S S E S Q R S R H G S V L S S N F T Y H T S D G D A L L L L C-term I G D I V V F G T V F L S I F Y S V I F A I G L V G N L L V V F A L T N S S V T D I Y L L N L A L S D L L F V A T L P F W T H Y L I N M C K F T T A F F F I G F F G S I F F I T V I S I D R Y L A I V L T V Q H G V T I S L G V W A A A I L V A A P Q F M F T L Q E I W P V L R N V E T N F L G F L L P L L I M S Y C Y F R I I Q T L F S C H K K A K A I K L I L L V V I V F F L F W T P Y N V M I F L E T L K L Y D S C D M R K D L R L A L S V T E T V A F S H C C L N P L I Y A F A G E K L Y H F R R Y L Y G K
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Residue Table


GPCRdb(A)
GPCRdb(A)
CX3CR1
TM2
2x48 2.48x48 L75
2x52 2.52x52 L79
TM4
4x47 4.47x47 L151
4x50 4.50x50 W154
4x54 4.54x54 I158