Structure information

GPR156

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

8IEP

SPECIES

Homo sapiens

RESOLUTION

2.610

PREFERRED CHAIN

C

REFERENCE

PUBLICATION DATE

Feb. 14, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
PC 34:1 L124 3.33x33 TM3 hydrophobic
PC 34:1 L127 3.36x36 TM3 hydrophobic
PC 34:1 C128 3.37x37 TM3 hydrophobic
PC 34:1 W183 4.50x50 TM4 hydrophobic
PC 34:1 I189 ECL2 hydrophobic
PC 34:1 F215 ECL2 hydrophobic
PC 34:1 A217 45.51x51 ECL2 hydrophobic
PC 34:1 I225 5.40x40 TM5 hydrophobic
PC 34:1 I228 5.43x43 TM5 hydrophobic
PC 34:1 W229 5.44x44 TM5 hydrophobic
PC 34:1 L236 5.51x51 TM5 hydrophobic
PC 34:1 L267 6.45x45 TM6 hydrophobic
PC 34:1 L274 6.52x52 TM6 hydrophobic
PC 34:1 R279 6.57x57 TM6 polar (charge-assisted hydrogen bond)
PC 34:1 I296 7.36x37 TM7 hydrophobic
PC 34:1 I296 7.36x37 TM7 Van der Waals
PC 34:1 C299 7.39x40 TM7 Van der Waals
PC 34:1 T300 7.40x41 TM7 Van der Waals

Ligands

PC 34:1

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Residue Diagrams

L I L L L G C S L F T W V I G L L V P S 1 I V T L L G S C L T Y S S A Y L F G I 2 G L I P G F V L S T G I C L M S L R T Q 3 L L G L V A A L L M A D V I L L M T W V 4 A L Y A G Y L L L L G K C G W I L A I W 5 V G V N L L V L A A G L L F V V T R Y L 6 C N I T T T C V F I G G S T L G F V L N 7
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ICL1 N R K R I V K M S ICL1ECL1 Q D V L ECL1ICL2 Q R V P D K R V I I ICL2ECL2 P I Q C L Q I L S V S M T V T G K D V S C T S T S T H F C A S R ECL2ICL3 S S P P V N Q ICL3ECL3 S ECL3N-term M E P E I N C S E L C D S F P G Q E L D R R P L H D L C K T T I T S S H H S S K T I S S L N-termC-term Y F S T P N K S F H T Q Y G E E E N C H P R G E K S S M E R L L T E K N A V I E S L Q E Q V N N A K E K I V R L M S A E C T Y D L P E G A A P P A S S P N K D V Q A V A S V H T L A A A Q G P S G H L S D F Q N D P G M A A R D S Q C T S G P S S Y A Q S L E G P G K D S S F S P G K E E K I S D S K D F S D H L D S G C S Q K P W T E Q S L G P E R G D Q V P M N P S Q S L L P E R G G S D P Q R Q R H L E N S E E P P E R R S R V S S V I R E K L Q E V L Q D L G L G P E A S L S T A P S C H Q Q T W K N S A A F S P Q K M P L S K E L G F S P Y M V R R R R A A Q R A R S H F P G S A P S S V G H R A N R T V P G A H S R L H V Q N G D S P S L A P Q T T D S R V R R P S S R K P S L P S D P Q D R P G T L E G S K Q S Q T E P E G A R G S K A A F L R Q P S G S G R A P S P A A P C L S K A S P D L P E Q W Q L W P P V P S G C A S L S S Q H S Y F D T E S S S S D E F F C R C H R P Y C E I C F Q S S S D S S D S G T S D T D P E P T G G L A S W E K L W A R S K P I V N F K D D L K P T L V C-term S P V L L G I V W T F L S C G L L L I L F F L A F T I H C S P N L N I V T L L G S C L T Y S S A Y L F G I V G S S M E T L I Q T R L S M L C I G T S L V F G P I L G K S W R L Y K V F T K D L Q L L G L V A A L L M A D V I L L M T W V L T D Y S D V W I A L I W G C K G L L L L Y G A Y L A G L T G H V S L T I M V G V N L L V L A A G L L F V V T R Y L H W P N L V F G L T S G G I F V C T T T I N C F I F I P Q L K Q W K A F E E E R R M N Q T I A K
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Residue Table


GPCRdb(A)
GPCRdb(C)
GPR156
TM3
3x29 3.33x33 L124
3x32 3.36x36 L127
3x33 3.37x37 C128
TM4
4x60 4.50x50 W183
ECL2
45x51 45.51x51 A217
TM5
5x40 5.40x40 I225
5x43 5.43x43 I228
5x44 5.44x44 W229
5x51 5.51x51 L236
TM6
6x43 6.45x45 L267
6x50 6.52x52 L274
6x55 6.57x57 R279
TM7
7x42 7.36x37 I296
7x45 7.39x40 C299
7x46 7.40x41 T300