Structure information

FFA3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8J21

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

D

REFERENCE

10.1038/S41422-023-00914-Z

PUBLICATION DATE

Jan. 24, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
butyric acid F96 3.33x33 TM3 hydrophobic
butyric acid V150 4.60x60 TM4 hydrophobic
butyric acid Y241 6.51x51 TM6 polar (hydrogen bond)
butyric acid Y241 6.51x51 TM6 Van der Waals
butyric acid H245 6.55x55 TM6 Van der Waals
butyric acid R258 7.35x34 TM7 polar (charge-assisted hydrogen bond)

Ligands

butyric acid

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Residue Diagrams

L N L P L G V L F T L L Y V S F V F W H 1 L N L T A S D L L L L L F L P F R M V 2 A A L F L A T L Y I T T F F I F G S L P 3 A G L V S V A C W L L A S A H C S V V Y 4 Y C Y S T I I L P V V F L V V A M E L R V 5 L A A T L L N F V L C F G P Y N V S H V V 6 F P D V C S N L T S L L T V Y I R W 7
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ICL1 P ICL1ECL1 E A A N G M H W P L ECL1ICL2 P L W Y K T R P ICL2ECL2 S G D I S H S Q G T N G T C Y L E F R K D ECL2ICL3 G G ICL3ECL3 E S P A ECL3N-term M D T G P D Q S Y F N-termC-term C G L W G Q W Q Q E S S M E L K E Q K G G E E Q R A D R P A E R K T S E H S Q G C G T G G Q V A C A E S C-term S G N H W F V F S V Y L L T F L V G L P L N L L A L V V F V G K L Q R R V A V D V L L L N L T A S D L L L L L F L P F R M V P F I L C P L S G F I F F T T I Y L T A L F L A A V S I E R F L S V A H R L G Q A G L V S V A C W L L A S A H C S V V Y V I E F Q L A I L L P V R L E M A V V L F V V P L I I T S Y C Y S R L V W I L G R S H R R Q R R V A G L L A A T L L N F L V C F G P Y N V S H V V G Y I C G W R I Y V T L L S T L N S C V D P F V Y Y F S S S G F H E L F Q A D L L R R
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Residue Table


GPCRdb(A)
GPCRdb(A)
FFA3 receptor
TM3
3x33 3.33x33 F96
TM4
4x60 4.60x60 V150
TM6
6x51 6.51x51 Y241
6x55 6.55x55 H245
TM7
7x34 7.35x34 R258