Structure information

FFA2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8J24

SPECIES

Homo sapiens

RESOLUTION

2.600

PREFERRED CHAIN

D

REFERENCE

10.1038/S41422-023-00914-Z

PUBLICATION DATE

Jan. 24, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
acetic acid Y90 3.33x33 TM3 hydrophobic
acetic acid Y165 45.51x51 ECL2 polar (charge-assisted hydrogen bond)
acetic acid R180 5.39x40 TM5 Van der Waals
acetic acid L183 5.42x43 TM5 Van der Waals
acetic acid Y238 6.51x51 TM6 polar (hydrogen bond)
acetic acid Y238 6.51x51 TM6 Van der Waals
acetic acid R255 7.34x33 TM7 Van der Waals

Ligands

acetic acid

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

L N A P L G T L F I I I Y A M L I L S S 1 L S L T L A D L L L L L L L P F K I I E 2 G A L L W T S C Y I S S Y F G F S T L A 3 G V I A A L V A W V M S F G H C T I V I 4 Y C F I T V A M P I F F L V L C L E L R V 5 A V V T L L N F V L C F G P Y N V S H L V 6 L P D L S A N L S S F V V A I S R W 7
Download: PNG | SVG
ICL1 P Q P ICL1ECL1 N F R W Y L ECL1ICL2 P V Q Y K L S R ICL2ECL2 T E Q V R S G N E I T C Y E N F T D N ECL2ICL3 P L V ICL3ECL3 K S P W ECL3N-term M L N-termC-term R N Q G S S L L G R R G K D T A E G T N E D R G V G Q G E G M P S S D F T T E C-term P D W K S S L I L M A Y I I I F L T G L P A N L L A L R A F V G R I R Q A P V H I L L L S L T L A D L L L L L L L P F K I I E A A S P K V V C A L T S F G F Y S S I Y C S T W L L A G I S I E R Y L G V A F R P L Y G V I A A L V A W V M S F G H C T I V I I V Q Y L N T Q L D V V L P V R L E L C L V L F F I P M A V T I F C Y W R F V W I M L S Q G A Q R R R R A V G L A V V T L L N F L V C F G P Y N V S H L V G Y H Q R W R S I A V V F S S L N A S L D P L L F Y F S S S V F G R L V R R A G L Q V
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
FFA2 receptor
TM3
3x33 3.33x33 Y90
ECL2
45x51 45.51x51 Y165
TM5
5x40 5.39x40 R180
5x43 5.42x43 L183
TM6
6x51 6.51x51 Y238
TM7
7x33 7.34x33 W254