Structure information

GPR161

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8SMV

SPECIES

Homo sapiens

RESOLUTION

2.740

PREFERRED CHAIN

R

REFERENCE

10.1101/2023.05.23.540554

PUBLICATION DATE

Feb. 21, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Cholesterol A278 6.43x43 TM6 hydrophobic
Cholesterol L326 7.55x55 TM7 hydrophobic
Cholesterol W327 7.56x56 TM7 hydrophobic

Ligands

Cholesterol

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Residue Diagrams

L N G L C V F I T I V I I A I F Q T I I 1 F S L T L S N F L L S L V V L P F V V T S 2 V G L T L M S A S S I L L Y L L A S F N 3 A V M A L V Y I W L H S L I G C L P P L 4 Y C V L M V L F P F L A C W I Q W F A T Y 5 L V V L G A F M V T W G P Y M V V I A S 6 L P H C V A S A F S L W T A W T E L S 7
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ICL1 S Y L L ICL1ECL1 E W I F ECL1ICL2 P M V Y P M K I ICL2ECL2 W S S V E F D E F K W M C V A A W H R ECL2ICL3 V V I V E E D A Q R T G R K N S S T S T S S S G S R R N A F Q G ICL3ECL3 G K S S V ECL3N-term M S L N S S L S C R K E L S N L T E E E G G N-termC-term F G D R Y Y R E P F V Q R Q R T S R L F S I S N R I T D L G L S P H L T A L M A G G Q P L G H S S S T G D T G F S C S Q D S G T D M M L L E D Y T S D D N P P S H C T C P P K R R S S V T F E D E V E Q I K E A A K N S I L H V K A E V H K S L D S Y A A S L A K A I E A E A K I N L F G E E A L P G V L V T A R T V P G G G F G G R R G S R T L V S Q R L Q L Q S I E E G D V L A A E Q R C-term E G G V I I T Q F I A I I V I T I F V C L G N L V I V V T L Y K K T L S N K F V F S L T L S N F L L S V L V L P F V V T S S I R R G V V W C N F S A L L Y L L I S S A S M L T L G V I A I D R Y Y A V L Y T G N R A V M A L V Y I W L H S L I G C L P P L F G E P G Y T A F W Q I W C A L F P F L V M L V C Y G F I F R V A R V K A R K V H C G T V V Y S A N Q C K A L I T I L V V L G A F M V T W G P Y M V V I A S E A L W S P S L E T W A T W L S F A S A V C H P L I Y G L W N K T L L G V R K E M C
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Residue Table


GPCRdb(A)
GPCRdb(A)
GPR161
TM6
6x43 6.43x43 A278
TM7
7x55 7.55x55 L326
7x56 7.56x56 W327