Structure information

GPR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8WW2

SPECIES

Homo sapiens

RESOLUTION

2.790

PREFERRED CHAIN

R

REFERENCE

10.1038/S41422-024-00932-5

PUBLICATION DATE

Feb. 14, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
oleic acid L116 3.32x32 TM3 hydrophobic
oleic acid F120 3.36x36 TM3 hydrophobic
oleic acid I124 3.40x40 TM3 hydrophobic
oleic acid V187 ECL2 hydrophobic
oleic acid L198 5.43x43 TM5 hydrophobic
oleic acid A201 5.46x46 TM5 hydrophobic
oleic acid W260 6.48x48 TM6 hydrophobic
oleic acid L283 7.39x38 TM7 hydrophobic

Ligands

oleic acid

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Residue Diagrams

A N E C S V L T G S I C L V V D W A K 1 G S L A V A D L L A G L G L V L H F A A 2 A L L S G I S A T F A M A L V G V L V L 3 T Y V M L A L V W G G A L G L G L L P 4 Y L Q L M I G F V M F F A I A L V V L H 5 A V V L G A F A A C W L P F T V Y C L L 6 I P N I M S N Y T A P L L T L Y T Y L 7
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ICL1 P A F R ICL1ECL1 C I G ECL1ICL2 A L T Y Y ICL2ECL2 V L A W N C L D G L T T C G V V Y P L ECL2ICL3 H L ICL3ECL3 D A H S ECL3N-term M M W G A G S P L A W L S A G S G N V N V S S V G P A E G P T G P A A P L P S P N-termC-term C C S S S K I P F R S R S P S D V C-term K A W D V V L C I S G T L V S C E N A L V V A I I V G T A P M F L L V G S L A V A D L L A G L G L V L H F A A V F S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N S E T T V T R T Y V M L A L V W G G A L G L G L L P S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R L P A S H Y V A T R K G I A T L A V V L G A F A A C W L P F T V Y C L L G P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D L W A V Q K V V C C
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Residue Table


GPCRdb(A)
GPCRdb(A)
GPR3
TM3
3x32 3.32x32 L116
3x36 3.36x36 F120
3x40 3.40x40 I124
TM5
5x43 5.43x43 L198
5x46 5.46x46 A201
TM6
6x48 6.48x48 W260
TM7
7x38 7.39x38 L283