Structure information

GPR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8X2K

SPECIES

Homo sapiens

RESOLUTION

3.030

PREFERRED CHAIN

A

REFERENCE

10.1038/S41422-023-00919-8

PUBLICATION DATE

April 3, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
N-oleoylethanolamide V113 3.29x29 TM3 hydrophobic
N-oleoylethanolamide A117 3.33x33 TM3 hydrophobic
N-oleoylethanolamide F120 3.36x36 TM3 hydrophobic
N-oleoylethanolamide I124 3.40x40 TM3 hydrophobic
N-oleoylethanolamide L198 5.43x43 TM5 hydrophobic
N-oleoylethanolamide A201 5.46x46 TM5 hydrophobic
N-oleoylethanolamide F202 5.47x47 TM5 hydrophobic
N-oleoylethanolamide W260 6.48x48 TM6 hydrophobic

Ligands

N-oleoylethanolamide

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Residue Diagrams

A N E C S V L T G S I C L V V D W A K 1 G S L A V A D L L A G L G L V L H F A A 2 A L L S G I S A T F A M A L V G V L V L 3 T Y V M L A L V W G G A L G L G L L P 4 Y L Q L M I G F V M F F A I A L V V L H 5 A V V L G A F A A C W L P F T V Y C L L 6 I P N I M S N Y T A P L L T L Y T Y L 7
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ICL1 P A F R ICL1ECL1 C I G ECL1ICL2 A L T Y Y ICL2ECL2 V L A W N C L D G L T T C G V V Y P L ECL2ICL3 H L ICL3ECL3 D A H S ECL3N-term M M W G A G S P L A W L S A G S G N V N V S S V G P A E G P T G P A A P L P S P N-termC-term C C S S S K I P F R S R S P S D V C-term K A W D V V L C I S G T L V S C E N A L V V A I I V G T A P M F L L V G S L A V A D L L A G L G L V L H F A A V F S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N S E T T V T R T Y V M L A L V W G G A L G L G L L P S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R L P A S H Y V A T R K G I A T L A V V L G A F A A C W L P F T V Y C L L G P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D L W A V Q K V V C C
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Residue Table


GPCRdb(A)
GPCRdb(A)
GPR3
TM3
3x29 3.29x29 V113
3x33 3.33x33 A117
3x36 3.36x36 F120
3x40 3.40x40 I124
TM5
5x43 5.43x43 L198
5x46 5.46x46 A201
5x47 5.47x47 F202
TM6
6x48 6.48x48 W260