Structure information

CXCR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8Y0N

SPECIES

Homo sapiens

RESOLUTION

3.070

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Feb. 26, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL2221034 W109 2.60x60 TM2 hydrophobic
CHEMBL2221034 F131 3.32x32 TM3 hydrophobic
CHEMBL2221034 F135 3.36x36 TM3 aromatic (face-to-edge)
CHEMBL2221034 W268 6.48x48 TM6 aromatic (face-to-edge)
CHEMBL2221034 Y271 6.51x51 TM6 aromatic (face-to-edge)
CHEMBL2221034 Y308 7.43x42 TM7 hydrophobic

Ligands

CHEMBL2221034

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Residue Diagrams

G N G L L G L L F L L S Y L A P L F A R 1 L H L A V A D T L L V L T L P L W A V D 2 C A L L L A G A Y F N I N F L A G A V K 3 V T L T C L A V W G L C L L F A L P D 4 Y C Y A M V L L P L L F G A V L Q L V R L 5 V V V V V A F A L C W T P Y H L V V L V 6 L P N L C C H M Y G L G S T V S K A V 7
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ICL1 R T A L ICL1ECL1 Q W V F ECL1ICL2 A T Q L Y R R G P P ICL2ECL2 S A H H D E R L N A T H C Q Y N F ECL2ICL3 R G Q ICL3ECL3 A L A R ECL3N-term M V L E V S D H Q V L N D A E V A A L L E N F S S S Y D Y G E N E S D S C C T S P P C P N-termC-term G C P N Q R G L Q R Q P S S S R R D S S W S E T S E A S Y S G L C-term Q D F S L N F D R A F L P A L Y S L L F L L G L L G N G A V A A V L L S R S S T D T F L L H L A V A D T L L V L T L P L W A V D A A V G S G L C K V A G A L F N I N F Y A G A L L L A C I S F D R Y L N I V H A R V T L T C L A V W G L C L L F A L P D F I F L P Q V G R T A L R V L Q L V A G F L L P L L V M A Y C Y A H I L A V L L V S R R L R A M R L V V V V V V A F A L C W T P Y H L V V L V D I L M D L G N C G R E S R V D V A K S V T S G L G Y M H C C L N P L L Y A F V G V K M W M L F R E R L L L R
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Residue Table


GPCRdb(A)
GPCRdb(A)
CXCR3
TM2
2x60 2.60x60 W109
TM3
3x32 3.32x32 F131
3x36 3.36x36 F135
TM6
6x48 6.48x48 W268
6x51 6.51x51 Y271
TM7
7x42 7.43x42 Y308