Structure information

oxoglutarate receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8YYX

SPECIES

Homo sapiens

RESOLUTION

2.840

PREFERRED CHAIN

E

REFERENCE

PUBLICATION DATE

April 9, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
LTE<sub>4</sub> L122 3.41x41 TM3 hydrophobic
LTE<sub>4</sub> C141 ICL2 Van der Waals
LTE<sub>4</sub> C141 ICL2 polar (hydrogen bond)
LTE<sub>4</sub> R148 4.40x40 TM4 polar (charge-assisted hydrogen bond)
LTE<sub>4</sub> C149 4.41x41 TM4 polar (hydrogen bond)
LTE<sub>4</sub> C149 4.41x41 TM4 Van der Waals
LTE<sub>4</sub> V152 4.44x44 TM4 hydrophobic
LTE<sub>4</sub> V152 4.44x44 TM4 Van der Waals
LTE<sub>4</sub> T205 5.45x46 TM5 Van der Waals

Ligands

LTE<sub>4</sub>

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Residue Diagrams

A N G P F G V L F I I G Y I V P L Y H M 1 L N L A C T D L L Y L T S L P F L I H Y 2 C T L F L I S S Y L N F H F S F R I F K 3 A V V A C A V V W I I S L V A V I P M 4 Y C L T V I V L P L C F T T A T L I L N Y 5 I L L L L A F Y V C F L P F H I L R V I 6 L L N G F T N L A A L P R S V I Y A E 7
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ICL1 M R P W ICL1ECL1 G E N W I F ECL1ICL2 P M S C F S I H ICL2ECL2 T S T N R T N R S A C L D L T S S D E ECL2ICL3 G L Q T ICL3ECL3 R L L S I ECL3N-term M N E P L D Y L A N A S D F P D Y A A A F G N C T D E N I P N-termC-term C K V S G N L E Q A K K I S Y S N N P C-term L K M H Y L P V I Y G I I F L V G F P G N A V V I S T Y I F K K S S T I I M L N L A C T D L L Y L T S L P F L I H Y Y A S G D F M C K F I R F S F H F N L Y S S I L F L T C F S I F R Y C V I I H K T R C A V V A C A V V W I I S L V A V I P M T F L I L N T I K W Y N L I L T A T T F C L P L V I V T L C Y T T I I H T L T H D S C L K Q K A R R L T I L L L L A F Y V C F L P F H I L R V I R I E S S C S I E N Q I H E A Y I V S R P L A A L N T F G N L L L Y V V V S D N V C S F Q Q A T V R
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Residue Table


GPCRdb(A)
GPCRdb(A)
oxoglutarate receptor
TM3
3x41 3.41x41 L122
TM4
4x40 4.40x40 R148
4x41 4.41x41 C149
4x44 4.44x44 V152
TM5
5x46 5.45x46 T205