Structure information

C3a receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8ZWG

SPECIES

Homo sapiens

RESOLUTION

2.870

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

May 14, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JR14a L30 1.39x39 TM1 hydrophobic
JR14a L82 2.64x64 TM2 hydrophobic
JR14a W88 23.50x50 ECL1 hydrophobic
JR14a I98 3.28x28 TM3 hydrophobic
JR14a I102 3.32x32 TM3 hydrophobic
JR14a R161 ECL2 polar (charge-assisted hydrogen bond)
JR14a Y174 45.52x52 ECL2 Van der Waals
JR14a Y174 45.52x52 ECL2 hydrophobic
JR14a R340 5.42x43 TM5 Van der Waals
JR14a Y393 6.51x51 TM6 polar (hydrogen bond with backbone)
JR14a Y393 6.51x51 TM6 polar (hydrogen bond)
JR14a G397 6.55x55 TM6 Van der Waals
JR14a D417 7.35x34 TM7 polar (charge-assisted hydrogen bond)
JR14a H418 7.36x35 TM7 Van der Waals
JR14a I421 7.39x38 TM7 Van der Waals
JR14a I421 7.39x38 TM7 hydrophobic

Ligands

JR14a

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Residue Diagrams

G N G P L G L L F T L S L I V M S L I V 1 L H L T L A D L L C C L S L P F S L A H 2 A T L L F V S A F M N L V I I S P I L K 3 A C S I C G C I W V V A F V M C I P V 4 Y C A I M I V S P L L F G V V L R T I T I 5 V V V V A V F L V C W T P Y H I F G V L 6 F P N F C S N A S A L A I C V H D W S 7
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ICL1 M Q R ICL1ECL1 G Q W P Y ECL1ICL2 P I W C Q N H R ICL2ECL2 E I F T T D N H N R C G Y K F G L S S S L D Y P D F Y G D P L E N R S L E N I V Q P P G E M N D R L D P S S F Q T N D H P W T V P T V F Q P Q T F Q R P S A D S L P R G S A R L T S Q N L Y S N V F K P A D V V S P K I P S G F P I E D H E T S P L D N S D A F L S T H L K L F P S A S S N S F Y E S E L P Q G F Q D Y Y N L G Q F T D D D Q ECL2ICL3 G R F A K S Q ICL3ECL3 D P E ECL3N-term M A S F S A E T N S T D L L S Q P W N N-termC-term S I Q G I L E A A F S E E L T R S T H C P S N N V I S E R N S T T V C-term E P P V I L S M V I L S L T F L L G L P G N G L V L W V A G L K T V N T I W F L H L T L A D L L C C L S L P F S L A H L A L Q G R F L C K L I P S I I V L N M F A S V F L L T A I S L D R C L V V F K N V G M A C S I C G C I W V V A F V M C I P V F V Y R V P T P L V A I T I T R L V V G F L L P S V I M I A C Y S F I V F R M Q R S K T F R V A V V V V A V F L V C W T P Y H I F G V L S L L T T P L G K T L M S W D H V C I A L A S A N S C F N P F L Y A L L G K D A R Q F R K K
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Residue Table


GPCRdb(A)
GPCRdb(A)
C3a receptor
TM1
1x39 1.39x39 L30
TM2
2x64 2.64x64 L82
ECL1
23x50 23.50x50 W88
TM3
3x28 3.28x28 I98
3x32 3.32x32 I102
ECL2
45x52 45.52x52 Y174
TM5
5x43 5.42x43 R340
TM6
6x51 6.51x51 Y393
6x55 6.55x55 G397
TM7
7x34 7.35x34 D417
7x35 7.36x35 H418
7x38 7.39x38 I421