Structure information

β2-adrenoceptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9CHU

SPECIES

Homo sapiens

RESOLUTION

3.490

PREFERRED CHAIN

A

REFERENCE

10.1073/PNAS.2414544121

PUBLICATION DATE

Nov. 13, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
(-)-noradrenaline D113 3.32x32 TM3 polar (charge-assisted hydrogen bond)
(-)-noradrenaline D113 3.32x32 TM3 polar (charge-charge)
(-)-noradrenaline V117 3.36x36 TM3 hydrophobic
(-)-noradrenaline V117 3.36x36 TM3 Van der Waals
(-)-noradrenaline S203 5.42x43 TM5 polar (hydrogen bond)
(-)-noradrenaline F412 6.51x51 TM6 hydrophobic
(-)-noradrenaline F412 6.51x51 TM6 Van der Waals
(-)-noradrenaline F413 6.52x52 TM6 Van der Waals
(-)-noradrenaline F413 6.52x52 TM6 hydrophobic
(-)-noradrenaline N435 7.39x38 TM7 polar (charge-assisted hydrogen bond)

Ligands

(-)-noradrenaline

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

V N G F V I A L V I L S M V I G M G V V 1 T S L A C A D L V M G A L V V P F G A A H 2 V C L T E I S A T V C L V D I S T W F E 3 A R V I I L M V W I V S G L T S F L P I 4 Y V F V M I V L P V Y F S V I S S A I A Y 5 G I I M G T F T L C W L P F F I V N I V 6 L P N F G S N V Y G I W N L L I Y V E 7
Download: PNG | SVG
ICL1 E R L Q ICL1ECL1 M W T F ECL1ICL2 P F K Y Q S L L ICL2ECL2 W Y R A T H Q E A I N C Y A N E T C C D F F T ECL2ICL3 G R F H V Q N L S Q V E Q D G R T G H G L R R S ICL3ECL3 D N L I ECL3N-term M G Q P G N G S A F L L A P N G S H A P D H D V T N-termC-term L R R S S L K A Y G N G Y S S N G N T G E Q S G Y H V E Q E K E N K L L C E D L P G T E D F V G H Q G T V P S D N I D S Q G R N C S T N D S L L C-term Q E R D E V W V V G M G I V M S L I V L A I V F G N V L V I T A I A K F T V T N Y F I T S L A C A D L V M G L A V V P F G A A H I L M K G N F W C E F W T S I D V L C V T A S I E T L C V I A V D R Y F A I T S T K N K A R V I I L M V W I V S G L T S F L P I Q M H N Q A Y A I A S S I V S F Y V P L V I M V F V Y S R V F Q E A K R Q L Q K I D K S E S K F C L K E H K A L K T L G I I M G T F T L C W L P F F I V N I V H V I Q R K E V Y I L L N W I G Y V N S G F N P L I Y C R S P D F Q E F R I A L L C
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
β2-adrenoceptor
TM3
3x32 3.32x32 D113
3x36 3.36x36 V117
TM5
5x43 5.42x43 S203
TM6
6x51 6.51x51 F289
6x52 6.52x52 F290
TM7
7x38 7.39x38 N312