Structure information

SST1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9IK9

SPECIES

Homo sapiens

RESOLUTION

3.370

PREFERRED CHAIN

D

REFERENCE

10.1016/J.APSB.2025.03.043

PUBLICATION DATE

April 30, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
LANREOTIDE T118 2.64x64 TM2 polar (hydrogen bond)
LANREOTIDE D137 3.32x32 TM3 polar (charge-assisted hydrogen bond)
LANREOTIDE M141 3.36x36 TM3 Van der Waals
LANREOTIDE A207 ECL2 Van der Waals
LANREOTIDE C208 45.50x50 ECL2 Van der Waals
LANREOTIDE C208 45.50x50 ECL2 polar (hydrogen bond with backbone)
LANREOTIDE N209 45.51x51 ECL2 polar (hydrogen bond)
LANREOTIDE M210 45.52x52 ECL2 Van der Waals
LANREOTIDE L220 5.35x36 TM5 polar (hydrogen bond)
LANREOTIDE L220 5.35x36 TM5 polar (hydrogen bond with backbone)
LANREOTIDE F223 5.38x39 TM5 polar (hydrogen bond)
LANREOTIDE V224 5.39x40 TM5 polar (hydrogen bond)
LANREOTIDE F287 6.51x51 TM6 hydrophobic
LANREOTIDE F287 6.51x51 TM6 Van der Waals
LANREOTIDE Q291 6.55x55 TM6 polar (hydrogen bond)
LANREOTIDE N294 6.58x58 TM6 Van der Waals
LANREOTIDE V295 6.59x59 TM6 Van der Waals
LANREOTIDE D300 ECL3 polar (charge-assisted hydrogen bond)
LANREOTIDE D301 ECL3 Van der Waals
LANREOTIDE A302 7.32x31 TM7 polar (hydrogen bond)
LANREOTIDE S305 7.35x34 TM7 polar (hydrogen bond)
LANREOTIDE V309 7.39x38 TM7 hydrophobic
LANREOTIDE V309 7.39x38 TM7 Van der Waals
LANREOTIDE Y313 7.43x42 TM7 polar (hydrogen bond)

Ligands

LANREOTIDE

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Residue Diagrams

S N G C L G V L C V V S Y I F S I L I A 1 L N L A I A D E L L M L S V P F L V T S 2 V T L C Y I S T F M N V A D V S L V L R 3 A K V V N L G V W V L S L L V I L P I 4 Y C L C I A G V P L L F G M L F T Y L V F 5 M M V V M V F V I C W M P F Y V V Q L V 6 I P N A C S N A Y G L I V S L Q S V T 7
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ICL1 A K M K ICL1ECL1 R H W P F ECL1ICL2 P I K A A R Y R ICL2ECL2 R T A A N S D G T V A C N M L M P E ECL2ICL3 W Q Q R K R S ICL3ECL3 E Q D ECL3N-term M F P N G T A S S P S S S P S P S P G S C G E G G G S R G P G A G A A D G M E E P G R N A S Q N G T L S N-termC-term L S W M D N A A E E P V D Y Y A T A L K S R A Y S V E D F Q P E N L E S G G V F R N G T C T S R I T T L C-term E G Q G S A I L I S F I Y S V V C L V G L C G N S M V I Y V I L R Y T A T N I Y I L N L A I A D E L L M L S V P F L V T S T L L G A L L C R L V L S V D A V N M F T S I Y C L T V L S V D R Y V A V V H R P T V A K V V N L G V W V L S L L V I L P I V V F S P A Q R W L V G F V L Y T F L M G F L L P V G A I C L C Y V L I I A K M R M V A L K A G E R K I T L M V M M V V M V F V I C W M P F Y V V Q L V N V F A D A T V S Q L S V I L G Y A N S C A N P I L Y G F L S D N F Q R F K R S I L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
SST1 receptor
TM2
2x64 2.64x64 T118
TM3
3x32 3.32x32 D137
3x36 3.36x36 M141
ECL2
45x50 45.50x50 C208
45x51 45.51x51 N209
45x52 45.52x52 M210
TM5
5x36 5.35x36 L220
5x39 5.38x39 F223
5x40 5.39x40 V224
TM6
6x51 6.51x51 F287
6x55 6.55x55 Q291
6x58 6.58x58 N294
6x59 6.59x59 V295
TM7
7x31 7.32x31 A302
7x34 7.35x34 S305
7x38 7.39x38 V309
7x42 7.43x42 Y313