Structure information

DP2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9IYB

SPECIES

Homo sapiens

RESOLUTION

2.820

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Dec. 4, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
PGD<sub>2</sub> F87 2.60x60 TM2 hydrophobic
PGD<sub>2</sub> F90 2.63x63 TM2 hydrophobic
PGD<sub>2</sub> H107 3.28x28 TM3 polar (hydrogen bond)
PGD<sub>2</sub> S108 3.29x29 TM3 Van der Waals
PGD<sub>2</sub> F111 3.32x32 TM3 hydrophobic
PGD<sub>2</sub> F111 3.32x32 TM3 Van der Waals
PGD<sub>2</sub> F112 3.33x33 TM3 hydrophobic
PGD<sub>2</sub> F112 3.33x33 TM3 Van der Waals
PGD<sub>2</sub> R170 4.64x65 TM4 polar (charge-assisted hydrogen bond)
PGD<sub>2</sub> I180 ECL2 polar (hydrogen bond with backbone)
PGD<sub>2</sub> I180 ECL2 Van der Waals
PGD<sub>2</sub> M181 ECL2 hydrophobic
PGD<sub>2</sub> M181 ECL2 Van der Waals
PGD<sub>2</sub> C182 45.50x50 ECL2 polar (hydrogen bond with backbone)
PGD<sub>2</sub> C182 45.50x50 ECL2 polar (hydrogen bond)
PGD<sub>2</sub> C182 45.50x50 ECL2 polar (hydrogen bond)
PGD<sub>2</sub> Y183 45.51x51 ECL2 Van der Waals
PGD<sub>2</sub> Y183 45.51x51 ECL2 hydrophobic
PGD<sub>2</sub> Y184 45.52x52 ECL2 polar (hydrogen bond)
PGD<sub>2</sub> Y184 45.52x52 ECL2 polar (hydrogen bond)
PGD<sub>2</sub> Y262 6.51x51 TM6 polar (hydrogen bond)
PGD<sub>2</sub> L286 7.35x34 TM7 hydrophobic
PGD<sub>2</sub> L286 7.35x34 TM7 Van der Waals
PGD<sub>2</sub> P287 7.36x35 TM7 Van der Waals
PGD<sub>2</sub> T290 7.39x38 TM7 polar (hydrogen bond)
PGD<sub>2</sub> F294 7.43x42 TM7 hydrophobic
PGD<sub>2</sub> F294 7.43x42 TM7 Van der Waals

Ligands

PGD<sub>2</sub>

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N E V L G L L S A L G H L L V A A H D 1 L H L A L S D L L A S A S L P F F T Y F 2 A S L L F G S A F M N L F F I S S H L K 3 A H K V C L V L W A L A V L N T V P Y 4 H S S A I I A L P V L F A L L F K S V A L 5 A A V V A A F A L C W G P Y H V F S L L 6 V P N A V S N F F A L S T V F P L G R 7
Download: PNG | SVG
ICL1 M R Q ICL1ECL1 H S W E L ECL1ICL2 P V W A Q N H R ICL2ECL2 D T I S R L D G R I M C Y Y N V L L L N P G P ECL2ICL3 G R R R ICL3ECL3 H A N P G ECL3N-term M S A N A T L K P L C P I L E Q M S R L Q S H S N T S I R Y I N-termC-term V L V D D S E L G G A G S S R R R R T S S T A R S A S P L A L C S R P E E P R G P A R L L G W L L G S C A A S P Q T G P L N R A L S S T S S C-term D H A A V L L H G L A S L L G L V E N G V I L F V V G C R T V V T T W V L H L A L S D L L A S A S L P F F T Y F L A V G G T T F C K L H S S I F F L N M F A S G F L L S A I S L D R C L Q V V R T V A A A H K V C L V L W A L A V L N T V P Y F V F R D R D A T C N S R Q V A L A V S K F L L A F L V P L A I I A S S H A A V S L R L Q H R P G R F V R L V A A V V A A F A L C W G P Y H V F S L L E A R A L R P L V W R G L P F V T S L A F F N S V A N P V L Y V L T C P D L R R V L E M L R K S L R T S
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
DP2 receptor
TM2
2x60 2.60x60 F87
2x63 2.63x63 F90
TM3
3x28 3.28x28 H107
3x29 3.29x29 S108
3x32 3.32x32 F111
3x33 3.33x33 F112
TM4
4x65 4.64x65 R170
ECL2
45x50 45.50x50 C182
45x51 45.51x51 Y183
45x52 45.52x52 Y184
TM6
6x51 6.51x51 Y262
TM7
7x34 7.35x34 L286
7x35 7.36x35 P287
7x38 7.39x38 T290
7x42 7.43x42 F294