Structure information

LPA1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9J5V

SPECIES

Homo sapiens

RESOLUTION

2.860

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Nov. 27, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CpY Q125 3.29x29 TM3 polar (hydrogen bond with backbone)
CpY Q125 3.29x29 TM3 Van der Waals
CpY Q125 3.29x29 TM3 polar (hydrogen bond)
CpY I128 3.32x32 TM3 hydrophobic
CpY I128 3.32x32 TM3 Van der Waals
CpY D129 3.33x33 TM3 polar (charge-assisted hydrogen bond)
CpY M198 ECL2 hydrophobic
CpY M198 ECL2 Van der Waals
CpY Y202 ECL2 hydrophobic
CpY W210 5.43x43 TM5 Van der Waals
CpY W210 5.43x43 TM5 hydrophobic
CpY W271 6.48x48 TM6 hydrophobic
CpY G274 6.51x51 TM6 Van der Waals
CpY L278 6.55x55 TM6 Van der Waals
CpY L278 6.55x55 TM6 hydrophobic
CpY E293 7.35x34 TM7 Van der Waals
CpY L297 7.39x38 TM7 Van der Waals
CpY L297 7.39x38 TM7 hydrophobic

Ligands

CpY

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Residue Diagrams

L N A L M I F I C V T I G L G M V L K S 1 A N L A A A D F F A G L A Y F Y L M F N 2 A L L N A V S A T L S T D I L G Q R L L 3 V V V V I V V I W T M A I V M G A I P S 4 Y L V V M V V F T V L N F I A W F V L Y 5 V I V L G A F I I C W T P G L V L L L L 6 I P N M A S N F E A L L L F F K E Y A 7
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ICL1 R R F H ICL1ECL1 T G P N T R R L ECL1ICL2 M Q L H T R M ICL2ECL2 W N C I C D I E N C S N M A P L Y ECL2ICL3 R H S S ICL3ECL3 P Q C ECL3N-term M A A I S T S I P V I S Q P Q F T A M N E P Q C F Y N E S I A F F Y N R S G K H L A T E W N N-termC-term C Q R S E N P T G P T E G S D R S A S S L N H T I L A G V H S N D H S V V C-term T V S K L V M G L G I T V C I F I M L A N L L V M V A I Y V N F P I Y Y L M A N L A A A D F F A G L A Y F Y L M F N T V S T W L L R Q G L I D T S L T A S V A N L L A I A I E R H I T V F R S N R R V V V V I V V I W T M A I V M G A I P S V G S D S Y L V F W A I F N L V T F V V M V V L Y A H I F G Y V R Q R T M R M S G P R R N R D T M M S L L K T V V I V L G A F I I C W T P G L V L L L L D V C C D V L A Y E K F F L L L A E F N S A M N P I I Y S Y R D K E F R Q M S A T I L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
LPA1 receptor
TM3
3x29 3.29x29 Q125
3x32 3.32x32 I128
3x33 3.33x33 D129
TM5
5x43 5.43x43 W210
TM6
6x48 6.48x48 W271
6x51 6.51x51 G274
6x55 6.55x55 L278
TM7
7x34 7.35x34 E293
7x38 7.39x38 L297