Structure information

MAS1

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9JLC

SPECIES

Homo sapiens

RESOLUTION

2.980

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Sept. 24, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
AVE 0991 L87 2.60x60 TM2 hydrophobic
AVE 0991 S109 3.29x29 TM3 polar (hydrogen bond)
AVE 0991 F112 3.32x32 TM3 Van der Waals
AVE 0991 Y251 6.58x58 TM6 polar (hydrogen bond)
AVE 0991 W255 ECL3 polar (hydrogen bond with backbone)
AVE 0991 W255 ECL3 Van der Waals
AVE 0991 H262 7.35x34 TM7 polar (hydrogen bond)
AVE 0991 H262 7.35x34 TM7 polar (hydrogen bond)
AVE 0991 H263 7.36x35 TM7 Van der Waals
AVE 0991 L266 7.39x38 TM7 polar (hydrogen bond)

Ligands

AVE 0991

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Residue Diagrams

G N E V F G V P S I S M I V W H V I P I 1 T H L S I A D I S L L F C I F I L S I D 2 A T L L Y L G T N Y G F L F T V S L T V 3 S A L V C A L L W A L S C L V T T M E Y 4 I T S S V L M L P T F V L F S L I A I F I 5 M V T I I I F L I F A M P M R L L Y L L 6 F P N A S S N I T S F L L S I H H L N 7
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ICL1 R R ICL1ECL1 Y E L ECL1ICL2 P I W Y R C H R ICL2ECL2 I D R E E E S H S R N ECL2ICL3 A S H ICL3ECL3 W S T F ECL3N-term M D G S N V T S F V V E E P T N I S T G R N A S V G N A H R Q N-termC-term L T R A F K D E M Q P R R Q K D N C N T V T V E T V V C-term I P I V H W V I M S I S P V G F V E N G I L L W F L C F R M N P F T V Y I T H L S I A D I S L L F C I F I L S I D Y A L D S S G H Y Y T I V T L S V T F L F G Y N T G L Y L L T A I S V E R C L S V L Y P K Y Q S A L V C A L L W A L S C L V T T M E Y V M C D C R A V I I F I A I L S F L V F T P L M L V S S T I L V V K I R K N T W S S K L Y I V I M V T I I I F L I F A M P M R L L Y L L Y Y E Y G N L H H I S L L F S T I N S S A N P F I Y F F V G S S F K E V K K K R S L K V
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Residue Table


GPCRdb(A)
GPCRdb(A)
MAS1
TM2
2x60 2.60x60 L87
TM3
3x29 3.29x29 S109
3x32 3.32x32 F112
TM6
6x58 6.58x58 Y251
TM7
7x34 7.35x34 H262
7x35 7.36x35 H263
7x38 7.39x38 L266