Structure information

TAS2R16

PROTEIN CLASS

Class T2 (Taste 2)

PDB CODE

9KPD

SPECIES

Homo sapiens

RESOLUTION

2.840

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELREP.2025.115604

PUBLICATION DATE

April 2, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
salicin W85 3.32x32 TM3 hydrophobic
salicin I247 6.56x56 TM6 hydrophobic
salicin K254 ECL3 polar (charge-assisted hydrogen bond)
salicin E262 7.39x38 TM7 polar (charge-assisted hydrogen bond)

Ligands

salicin

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Residue Diagrams

S S Q V I I T L S E L V Y I I M F F V T 1 I S L G I S R F C L Q W A S M L N N F C 2 L S N L W F T L I N F F E W T I T L N C 3 F P W I L L G S L M I T C V T I I P S A 4 T S A L F L I F P I V L A V T H A Q F Q 5 L A V L F I V F T S Y F L T I L I T I I 6 T S H M L I F A Y V F A E W V W L W C 7
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ICL1 R L ICL1ECL1 L N Y ECL1ICL2 S F T H H I F L W L R W ICL2ECL2 I Q I Q L L T M E H L P R N S T V T D K L E N F H Q Y ECL2ICL3 C ICL3ECL3 D K ECL3N-term M I N-term P I Q L T V F F M I I Y V L E S L T I I V Q S S L I V A V L G R E W L Q V R M P V D M I L I S L G I S R F C L Q W A S M L N N F C S Y F N V L C N L T I T W E F F N I L T F W L N S L L T V F Y C I K V S R I L R L F P W I L L G S L M I T C V T I I P S A I G N Y Q F Q A H T V A L V I P F I L F L A S T I F L M A S L T K Q I Q H H S T G H N P S M K A R F T A L R S L A V L F I V F T S Y F L T I L I T I I G T L F R C W L W V W E A F V Y A F I L M H S T S L M L S S P T L K G L K R I K C
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Residue Table


GPCRdb(A)
GPCRdb(A)
TAS2R16
TM3
3x32 3.32x32 W85
TM6
6x56 6.56x56 I247
TM7
7x38 7.39x38 E262