Structure information

C3a receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9KUT

SPECIES

Homo sapiens

RESOLUTION

3.290

PREFERRED CHAIN

C

REFERENCE

PUBLICATION DATE

Nov. 26, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JR14a L30 1.39x39 TM1 hydrophobic
JR14a F77 2.59x59 TM2 hydrophobic
JR14a I98 3.28x28 TM3 hydrophobic
JR14a I102 3.32x32 TM3 hydrophobic
JR14a Y174 45.52x52 ECL2 Van der Waals
JR14a Y174 45.52x52 ECL2 polar (hydrogen bond)
JR14a Y393 6.51x51 TM6 hydrophobic
JR14a Y393 6.51x51 TM6 Van der Waals
JR14a F396 6.54x54 TM6 Van der Waals
JR14a G397 6.55x55 TM6 polar (hydrogen bond with backbone)
JR14a G397 6.55x55 TM6 Van der Waals
JR14a D417 7.35x34 TM7 polar (charge-assisted hydrogen bond)
JR14a I421 7.39x38 TM7 hydrophobic
JR14a I421 7.39x38 TM7 Van der Waals
JR14a A422 7.40x39 TM7 Van der Waals

Ligands

JR14a

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Residue Diagrams

G N G P L G L L F T L S L I V M S L I V 1 L H L T L A D L L C C L S L P F S L A H 2 A T L L F V S A F M N L V I I S P I L K 3 A C S I C G C I W V V A F V M C I P V 4 Y C A I M I V S P L L F G V V L R T I T I 5 V V V V A V F L V C W T P Y H I F G V L 6 F P N F C S N A S A L A I C V H D W S 7
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ICL1 M Q R ICL1ECL1 G Q W P Y ECL1ICL2 P I W C Q N H R ICL2ECL2 E I F T T D N H N R C G Y K F G L S S S L D Y P D F Y G D P L E N R S L E N I V Q P P G E M N D R L D P S S F Q T N D H P W T V P T V F Q P Q T F Q R P S A D S L P R G S A R L T S Q N L Y S N V F K P A D V V S P K I P S G F P I E D H E T S P L D N S D A F L S T H L K L F P S A S S N S F Y E S E L P Q G F Q D Y Y N L G Q F T D D D Q ECL2ICL3 G R F A K S Q ICL3ECL3 D P E ECL3N-term M A S F S A E T N S T D L L S Q P W N N-termC-term S I Q G I L E A A F S E E L T R S T H C P S N N V I S E R N S T T V C-term E P P V I L S M V I L S L T F L L G L P G N G L V L W V A G L K T V N T I W F L H L T L A D L L C C L S L P F S L A H L A L Q G R F L C K L I P S I I V L N M F A S V F L L T A I S L D R C L V V F K N V G M A C S I C G C I W V V A F V M C I P V F V Y R V P T P L V A I T I T R L V V G F L L P S V I M I A C Y S F I V F R M Q R S K T F R V A V V V V A V F L V C W T P Y H I F G V L S L L T T P L G K T L M S W D H V C I A L A S A N S C F N P F L Y A L L G K D A R Q F R K K
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Residue Table


GPCRdb(A)
GPCRdb(A)
C3a receptor
TM1
1x39 1.39x39 L30
TM2
2x59 2.59x59 F77
TM3
3x28 3.28x28 I98
3x32 3.32x32 I102
ECL2
45x52 45.52x52 Y174
TM6
6x51 6.51x51 Y393
6x54 6.54x54 F396
6x55 6.55x55 G397
TM7
7x34 7.35x34 D417
7x38 7.39x38 I421
7x39 7.40x39 A422