Structure information

OR6C76

PROTEIN CLASS

Class O2 (Olfactory/extra-nasal 2)

PDB CODE

9LDZ

SPECIES

Homo sapiens

RESOLUTION

3.170

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Jan. 28, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Cholesterol W70 2.52x52 TM2 hydrophobic
Cholesterol V74 2.56x56 TM2 hydrophobic
Cholesterol F101 3.31x31 TM3 hydrophobic
ethyl (2R,3S)-3-methyl-3-phenyl-oxirane-2-carboxylate I103 3.33x33 TM3 hydrophobic
ethyl (2R,3S)-3-methyl-3-phenyl-oxirane-2-carboxylate I153 4.56x56 TM4 hydrophobic
ethyl (2R,3S)-3-methyl-3-phenyl-oxirane-2-carboxylate L200 5.42x42 TM5 hydrophobic
ethyl (2R,3S)-3-methyl-3-phenyl-oxirane-2-carboxylate Y257 6.55x55 TM6 hydrophobic

Ligands

Cholesterol

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ethyl (2R,3S)-3-methyl-3-phenyl-oxirane-2-carboxylate

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Residue Diagrams

L N G T V S L V Y T L F L F S F I V V Q 1 R N F S L E I S F T S V C N P R F L I 2 S A L L F F E T S G L F I F F F L Q A A 3 C Y Q L I I S S W L A G F L V I F P P L 4 Y S L I V L I L T S I L T F L A L I F S 5 S S H V I V V S I S Y G S C I F M Y V 6 F P N L M P A V S T N L I A V G K T L 7
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ICL1 S H L K ICL1ECL1 D K S I ECL1ICL2 P L H Y T T I M ICL2ECL2 Q L D F C D S N V I D H F T C D S A P L L Q I S C T D ECL2ICL3 I P ICL3ECL3 K T ECL3N-term M K N R T S V T D F I L L G L T D N-termC-term K H C-term N P Q L Q V V I F S F L F L T Y V L S V T G N L T I I S L T L L D T P M Y F F L R N F S L E I S F T S V C N P R F L I S I L T G S Y N A C A A Q L F F F I F L G S T E F F L L A S M S Y D C Y V A I C K S D R I C Y Q L I I S S W L A G F L V I F P P L A M G L T S T L E L M S F I L A L F T L I S T L I L V I L S Y T Y I I R T I L R S A Q Q R K K A F S T C S S H V I V V S I S Y G S C I F M Y V S A K E G V A L T K G V A I L N T S V A P M L N P F I Y T L R N Q Q F K D I S H V K Q A V L R K K K K
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Residue Table


GPCRdb(A)
GPCRdb(A)
OR6C76
TM2
2x52 2.52x52 S69
2x56 2.56x56 V73
TM3
3x31 3.31x31 F100
3x33 3.33x33 I102
TM4
4x56 4.56x56 V152
TM5
5x42 5.42x42 L199
TM6
6x55 6.55x55 Y256