Structure information

B2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9LFD

SPECIES

Homo sapiens

RESOLUTION

3.600

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

May 27, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
WIN 64338 W113 2.60x60 TM2 hydrophobic
WIN 64338 F121 ECL1 aromatic (face-to-edge)
WIN 64338 W123 23.50x50 ECL1 hydrophobic
WIN 64338 V133 3.28x28 TM3 hydrophobic
WIN 64338 N134 3.29x29 TM3 polar (hydrogen bond)
WIN 64338 I137 3.32x32 TM3 Van der Waals
WIN 64338 I137 3.32x32 TM3 hydrophobic
WIN 64338 M192 4.60x61 TM4 Van der Waals
WIN 64338 Y201 ECL2 hydrophobic
WIN 64338 Y201 ECL2 Van der Waals
WIN 64338 C211 45.50x50 ECL2 Van der Waals
WIN 64338 W285 6.48x48 TM6 Van der Waals
WIN 64338 W285 6.48x48 TM6 hydrophobic
WIN 64338 F288 6.51x51 TM6 aromatic (face-to-edge)
WIN 64338 F288 6.51x51 TM6 Van der Waals
WIN 64338 Q317 7.36x35 TM7 Van der Waals
WIN 64338 S320 7.39x38 TM7 Van der Waals
WIN 64338 A323 7.42x41 TM7 Van der Waals
WIN 64338 Y324 7.43x42 TM7 Van der Waals
WIN 64338 Y324 7.43x42 TM7 aromatic (face-to-edge)

Ligands

WIN 64338

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Residue Diagrams

I N E L T A L V F L V W L F P P Q I T N 1 G N L A A A D L I L A C G L P F W A I T 2 L M L F C I S S Y L N M S I I A N V V R 3 A K L Y S L V I W G C T L L L S S P M 4 T C F T I V S L P L L F G V V N L L M N T 5 L V V L L L F I I C W L P F Q I S T F L 6 L P N L C S N S Y A M F S A I Q T I V 7
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ICL1 K S S C ICL1ECL1 F D W L F ECL1ICL2 T M S M G R M R ICL2ECL2 T M K E Y S D E G H N V T A C V I S Y P ECL2ICL3 F K E ICL3ECL3 I L S ECL3N-term M F S P W K I S M F L S V R E D S V P T T A S F S A D M L N V T L Q G P T L N G T F A Q S K C P Q V E W L G N-termC-term Y Q G V C Q K G G C R S E P I Q M E N S M G T L R T S I S V E R Q I H K L Q D W A G S R Q C-term W L N T I Q P P F L W V L F V L A T L E N I F V L S V F C L H T V A E I Y L G N L A A A D L I L A C G L P F W A I T I S N N G E T L C R V V N A I I S M N L Y S S I C F L M L V S I D R Y L A L V K G V R W A K L Y S L V I W G C T L L L S S P M L V F R S L I W E V F T N M L L N V V G F L L P L S V I T F C T M Q I M Q V L R N N E M Q K I Q T E R R A T V L V L V V L L L F I I C W L P F Q I S T F L D T L H R L G S C Q D E R I I D V I T Q I A S F M A Y S N S C L N P L V Y V I V G K R S W E F R K K V
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Residue Table


GPCRdb(A)
GPCRdb(A)
B2 receptor
TM2
2x60 2.60x60 W113
ECL1
23x50 23.50x50 W123
TM3
3x28 3.28x28 V133
3x29 3.29x29 N134
3x32 3.32x32 I137
TM4
4x61 4.60x61 M192
ECL2
45x50 45.50x50 C211
TM6
6x48 6.48x48 W283
6x51 6.51x51 F286
TM7
7x35 7.36x35 Q315
7x38 7.39x38 S318
7x41 7.42x41 A321
7x42 7.43x42 Y322