Structure information

GPR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9M88

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Sept. 24, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
N-oleoylethanolamide F120 3.36x36 TM3 hydrophobic
N-oleoylethanolamide I124 3.40x40 TM3 hydrophobic
N-oleoylethanolamide L198 5.43x43 TM5 hydrophobic
N-oleoylethanolamide F202 5.47x47 TM5 hydrophobic
AF64394 Q211 5.56x56 TM5 polar (hydrogen bond)
AF64394 Q211 5.56x56 TM5 polar (hydrogen bond)
AF64394 Q211 5.56x56 TM5 Van der Waals
AF64394 A214 5.59x59 TM5 Van der Waals
AF64394 Q215 5.60x60 TM5 Van der Waals
AF64394 R218 5.63x63 TM5 polar (charge-assisted hydrogen bond)
N-oleoylethanolamide W260 6.48x48 TM6 hydrophobic
N-oleoylethanolamide F263 6.51x51 TM6 hydrophobic
N-oleoylethanolamide L283 7.39x38 TM7 hydrophobic

Ligands

N-oleoylethanolamide

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AF64394

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Residue Diagrams

A N E C S V L T G S I C L V V D W A K 1 G S L A V A D L L A G L G L V L H F A A 2 A L L S G I S A T F A M A L V G V L V L 3 T Y V M L A L V W G G A L G L G L L P 4 Y L Q L M I G F V M F F A I A L V V L H 5 A V V L G A F A A C W L P F T V Y C L L 6 I P N I M S N Y T A P L L T L Y T Y L 7
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ICL1 P A F R ICL1ECL1 C I G ECL1ICL2 A L T Y Y ICL2ECL2 V L A W N C L D G L T T C G V V Y P L ECL2ICL3 H L ICL3ECL3 D A H S ECL3N-term M M W G A G S P L A W L S A G S G N V N V S S V G P A E G P T G P A A P L P S P N-termC-term C C S S S K I P F R S R S P S D V C-term K A W D V V L C I S G T L V S C E N A L V V A I I V G T A P M F L L V G S L A V A D L L A G L G L V L H F A A V F S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N S E T T V T R T Y V M L A L V W G G A L G L G L L P S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R L P A S H Y V A T R K G I A T L A V V L G A F A A C W L P F T V Y C L L G P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D L W A V Q K V V C C
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Residue Table


GPCRdb(A)
GPCRdb(A)
GPR3
TM3
3x36 3.36x36 F120
3x40 3.40x40 I124
TM5
5x43 5.43x43 L198
5x47 5.47x47 F202
5x56 5.56x56 Q211
5x59 5.59x59 A214
5x60 5.60x60 Q215
5x63 5.63x63 R218
TM6
6x48 6.48x48 W260
6x51 6.51x51 F263
TM7
7x38 7.39x38 L283