Structure information

mGlu8 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

9MBC

SPECIES

Homo sapiens

RESOLUTION

2.970

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Oct. 1, 2025

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
(<i>S</i>)-3,4-DCPG R75 N-term polar (charge-assisted hydrogen bond)
(<i>S</i>)-3,4-DCPG A154 N-term hydrophobic
(<i>S</i>)-3,4-DCPG A154 N-term Van der Waals
(<i>S</i>)-3,4-DCPG S156 N-term polar (hydrogen bond)
(<i>S</i>)-3,4-DCPG S156 N-term polar (hydrogen bond)
(<i>S</i>)-3,4-DCPG S156 N-term polar (hydrogen bond with backbone)
(<i>S</i>)-3,4-DCPG A177 N-term Van der Waals
(<i>S</i>)-3,4-DCPG A177 N-term polar (hydrogen bond with backbone)
(<i>S</i>)-3,4-DCPG S178 N-term Van der Waals
(<i>S</i>)-3,4-DCPG T179 N-term polar (hydrogen bond with backbone)
(<i>S</i>)-3,4-DCPG T179 N-term polar (hydrogen bond)
(<i>S</i>)-3,4-DCPG T179 N-term polar (hydrogen bond)
(<i>S</i>)-3,4-DCPG T179 N-term Van der Waals
(<i>S</i>)-3,4-DCPG Y227 N-term hydrophobic
(<i>S</i>)-3,4-DCPG Y227 N-term Van der Waals
(<i>S</i>)-3,4-DCPG D309 N-term polar (charge-assisted hydrogen bond)
(<i>S</i>)-3,4-DCPG S310 N-term Van der Waals
(<i>S</i>)-3,4-DCPG K314 N-term polar (charge-assisted hydrogen bond)
AZ12216052 W583 N-term hydrophobic
AZ12216052 I800 6.56x56 TM6 hydrophobic
AZ12216052 I813 7.27x28 TM7 hydrophobic
AZ12216052 V820 7.34x35 TM7 hydrophobic

Ligands

(<i>S</i>)-3,4-DCPG

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


AZ12216052

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

T T A I I G L I A V F V P V V A W 1 Y V L L T G I F L C Y S I T F L M I A 2 T L L A A Y S F C M G L G L F V R R F S 3 Q L V I T F S L I S V Q L L G V F V W F 4 A Y V T C T V M L L I S Y G L S C I L S 5 G F T M Y T T C I I W L A F I P I F F G 6 G L S V S A S L S M S V T L T T T Q I 7
Download: PNG | SVG
ICL1 T N D P I V R A S ICL1ECL1 A P ECL1ICL2 G K K S V T A P K F I ICL2ECL2 P P H I I I D Y G E Q R T L D P E K A R G V L K C D I ECL2ICL3 G V P E T ICL3ECL3 A Q S A E K M Y ECL3N-term M V C E G K R S A S C P C F F L L T A K F Y W I L T M M Q R T H S Q E Y A H S I R V D G D I I L G G L F P V H A K G E R G V P C G E L K K E K G I H R L E A M L Y A I D Q I N K D P D L L S N I T L G V R I L D T C S R D T Y A L E Q S L T F V Q A L I E K D A S D V K C A N G D P P I F T K P D K I S G V I G A A A S S V S I M V A N I L R L F K I P Q I S Y A S T A P E L S D N T R Y D F F S R V V P P D S Y Q A Q A M V D I V T A L G W N Y V S T L A S E G N Y G E S G V E A F T Q I S R E I G G V C I A Q S Q K I P R E P R P G E F E K I I K R L L E T P N A R A V I M F A N E D D I R R I L E A A K K L N Q S G H F L W I G S D S W G S K I A P V Y Q Q E E I A E G A V T I L P K R A S I D G F D R Y F R S R T L A N N R R N V W F A E F W E E N F G C K L G S H G K R N S H I K K C T G L E R I A R D S S Y E Q E G K V Q F V I D A V Y S M A Y A L H N M H K D L C P G Y I G L C P R M S T I D G K E L L G Y I R A V N F N G S A G T P V T F N E N G D A P G R Y D I F Q Y Q I T N K S T E Y K V I G H W T N Q L H L K V E D M Q W A H R E H T H P A S V C S L P C K P G E R K K T V K G V P C C W H C E R C E G Y N Y Q V D E L S C E L C P L D Q R P N M N R T G C Q L I P I I K L E W H S P N-termC-term K A V V T A A T M Q S K L I Q K G N D R P N G E V K S E L C E S L E T N T S S T K T T Y I S Y S N H S I C-term W A V V P V F V A I L G I I A T T F V I V T F V R Y G R E L S Y V L L T G I F L C Y S I T F L M I A D T I I C S F R R V F L G L G M C F S Y A A L L T K T N R I H R I F E Q S P A S Q L V I T F S L I S V Q L L G V F V W F V V D S D L S L I C S L G Y S I L L M V T C T V Y A I K T R F N E A K P I G F T M Y T T C I I W L A F I P I F F G T I Q T T T L T V S M S L S A S V S L G M L Y M P K V Y I I I F H P E Q R K R N V Q K S F
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu8 receptor
TM6
6x54 6.56x56 I800
TM7
7x33 7.27x28 I813
7x40 7.34x35 V820