Structure information

TAS2R43

PROTEIN CLASS

Class T2 (Taste 2)

PDB CODE

9OXA

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

R

REFERENCE

10.1038/S41594-026-01776-W

PUBLICATION DATE

April 22, 2026

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
aristolochic acid L62 2.57x57 TM2 hydrophobic
aristolochic acid N65 2.60x60 TM2 polar (hydrogen bond)
aristolochic acid N65 2.60x60 TM2 Van der Waals
aristolochic acid A84 3.28x28 TM3 hydrophobic
aristolochic acid A84 3.28x28 TM3 Van der Waals
aristolochic acid Y85 3.29x29 TM3 Van der Waals
aristolochic acid Y85 3.29x29 TM3 hydrophobic
aristolochic acid W88 3.32x32 TM3 aromatic (face-to-face)
aristolochic acid W88 3.32x32 TM3 Van der Waals
aristolochic acid T180 5.43x44 TM5 Van der Waals
aristolochic acid S248 6.55x55 TM6 polar (charge-assisted hydrogen bond)
aristolochic acid F252 6.59x59 TM6 aromatic (face-to-face)
aristolochic acid F252 6.59x59 TM6 Van der Waals
aristolochic acid K265 7.39x38 TM7 Van der Waals
aristolochic acid R268 7.42x41 TM7 polar (charge-charge)
aristolochic acid R268 7.42x41 TM7 polar (charge-assisted hydrogen bond)

Ligands

aristolochic acid

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N A F N G I V F T V V V L S S F I I P 1 T A L A V S R V G L L W V L L L N W Y S 2 T T A L W N S F H N I V A W I N Y A T T 3 I L V M L L G P L L F L A C H L F V I N 4 F S L L T L T F P V L N A V M T V T M N 5 V I S F L L L C A I Y F L S I M I S V W 6 F P H I S P Y S F R I A K C F M F V P 7
Download: PNG | SVG
ICL1 K I ICL1ECL1 P A F N ECL1ICL2 N F S N F I F L H L K R ICL2ECL2 V R T K E F E G N M T W K I K L K S A M Y F S ECL2ICL3 K G S Q ICL3ECL3 L E N ECL3N-term M N-termC-term K G E K T S S P C-term I T F L P I I F S S L V V V T F V I G N F A N G F I A L V N S I E W F K R Q S F A D Q I L T A L A V S R V G L L W V L L L N W Y S T V L N S V E V R T T A Y N I W A V I N H F S N W L A T T L S I F Y L L K I A R V K S V I L V M L L G P L L F L A C H L F V I N M N E I N M T V T M V A N L V P F T L T L L S F M L L I C S L C K H L K K M Q L H G D P S T K V H I K A L Q T V I S F L L L C A I Y F L S I M I S V W S F G S K P V F M F C K A I R F S Y P S I H P F I L I W G N K K F L S M R Y L K Q T V F W Q W V
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
TAS2R43
TM2
2x57 2.57x57 L62
2x60 2.60x60 N65
TM3
3x28 3.28x28 A84
3x29 3.29x29 Y85
3x32 3.32x32 W88
TM5
5x44 5.43x44 T180
TM6
6x55 6.55x55 S248
6x59 6.59x59 F252
TM7
7x38 7.39x38 K265
7x41 7.42x41 R268