Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9P89

SPECIES

Homo sapiens

RESOLUTION

3.900

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-026-10120-7

PUBLICATION DATE

March 25, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
NTS8–13 H132 ECL1 polar (hydrogen bond with backbone)
NTS8–13 H132 ECL1 Van der Waals
NTS8–13 V223 ECL2 Van der Waals
NTS8–13 V223 ECL2 hydrophobic
NTS8–13 C224 45.50x50 ECL2 Van der Waals
NTS8–13 T225 45.51x51 ECL2 Van der Waals
NTS8–13 D331 ECL3 Van der Waals
NTS8–13 W334 ECL3 Van der Waals
NTS8–13 Y339 7.28x27 TM7 hydrophobic
NTS8–13 Y339 7.28x27 TM7 Van der Waals

Ligands

NTS8–13

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Residue Diagrams

T N G V T G V V F L A L Y V A T V L V K 1 G S L A L S D L L T L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A V P M 4 N L V S I V V M P F I F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I T S S V Y F L A N T V M Y F Y 7
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ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G E Q N R S A D G Q H A G G L V C T P T I ECL2ICL3 Q V C T V G G E H S T F S M A I E ICL3ECL3 S D E Q W ECL3N-term M R L N S S A P G T P G T P A A D P F Q R A Q A G L E E A L L A P G F G N A S G N A S E R V L A A P S S E L D V N T N-termC-term P V W R R R R K R P A F S R K A D S V S S N H T L S S N A T R E T L Y C-term D I Y S K V L V T A V Y L A L F V V G T V G N T V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L T L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A V P M L F T M H T A T V K V V I Q V N T F M S F I F P M V V I S V L N T I I A N K L T V M V R Q A A E Q G P G R V Q A L R H G V R V L R A V V I A F V V C W L P Y H V R R L M F C Y I T P F L Y D F Y H Y F Y M V T N A L F Y V S S T I N P I L Y N L V S A N F L A L C F R H I T L A C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
ECL2
45x50 45.50x50 C224
45x51 45.51x51 T225
TM7
7x27 7.28x27 Y339