Structure information

oxoglutarate receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9VMO

SPECIES

Homo sapiens

RESOLUTION

2.400

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELL.2026.01.036

PUBLICATION DATE

March 18, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Itaconic acid Y40 1.39x39 TM1 polar (hydrogen bond)
Itaconic acid Y93 2.64x64 TM2 polar (hydrogen bond)
Itaconic acid Y93 2.64x64 TM2 Van der Waals
Itaconic acid R110 3.29x29 TM3 polar (charge-assisted hydrogen bond)
Itaconic acid F113 3.32x32 TM3 hydrophobic
Itaconic acid F113 3.32x32 TM3 Van der Waals
Itaconic acid H114 3.33x33 TM3 polar (hydrogen bond)
Itaconic acid H114 3.33x33 TM3 Van der Waals
Itaconic acid D185 45.52x52 ECL2 Van der Waals
Itaconic acid R288 7.39x38 TM7 polar (charge-assisted hydrogen bond)

Ligands

Itaconic acid

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Residue Diagrams

A N G P F G V L F I I G Y I V P L Y H M 1 L N L A C T D L L Y L T S L P F L I H Y 2 C T L F L I S S Y L N F H F S F R I F K 3 A V V A C A V V W I I S L V A V I P M 4 Y C L T V I V L P L C F T T A T L I L N Y 5 I L L L L A F Y V C F L P F H I L R V I 6 L L N G F T N L A A L P R S V I Y A E 7
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ICL1 M R P W ICL1ECL1 G E N W I F ECL1ICL2 P M S C F S I H ICL2ECL2 T S T N R T N R S A C L D L T S S D E ECL2ICL3 G L Q T ICL3ECL3 R L L S I ECL3N-term M N E P L D Y L A N A S D F P D Y A A A F G N C T D E N I P N-termC-term C K V S G N L E Q A K K I S Y S N N P C-term L K M H Y L P V I Y G I I F L V G F P G N A V V I S T Y I F K K S S T I I M L N L A C T D L L Y L T S L P F L I H Y Y A S G D F M C K F I R F S F H F N L Y S S I L F L T C F S I F R Y C V I I H K T R C A V V A C A V V W I I S L V A V I P M T F L I L N T I K W Y N L I L T A T T F C L P L V I V T L C Y T T I I H T L T H D S C L K Q K A R R L T I L L L L A F Y V C F L P F H I L R V I R I E S S C S I E N Q I H E A Y I V S R P L A A L N T F G N L L L Y V V V S D N V C S F Q Q A T V R
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Residue Table


GPCRdb(A)
GPCRdb(A)
oxoglutarate receptor
TM1
1x39 1.39x39 Y40
TM2
2x64 2.64x64 Y93
TM3
3x29 3.29x29 R110
3x32 3.32x32 F113
3x33 3.33x33 H114
ECL2
45x52 45.52x52 D185
TM7
7x38 7.39x38 R288