Structure information

NK2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9W2G

SPECIES

Homo sapiens

RESOLUTION

3.400

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

June 17, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
EB1001 A25 N-term hydrophobic
EB1001 F26 N-term hydrophobic
EB1001 N86 2.57x57 TM2 polar (hydrogen bond)
EB1001 N86 2.57x57 TM2 Van der Waals
EB1001 N90 2.61x61 TM2 polar (hydrogen bond)
EB1001 N90 2.61x61 TM2 polar (hydrogen bond)
EB1001 Y93 2.64x64 TM2 Van der Waals
EB1001 Y93 2.64x64 TM2 hydrophobic
EB1001 N97 2.68x68 TM2 polar (hydrogen bond)
EB1001 N97 2.68x68 TM2 Van der Waals
EB1001 I114 3.33x33 TM3 hydrophobic
EB1001 I114 3.33x33 TM3 Van der Waals
EB1001 K180 ECL2 polar (charge-assisted hydrogen bond)
EB1001 V182 45.51x51 ECL2 hydrophobic
EB1001 V182 45.51x51 ECL2 Van der Waals
EB1001 Y266 6.51x51 TM6 polar (hydrogen bond)
EB1001 Y269 6.54x54 TM6 Van der Waals
EB1001 F270 6.55x55 TM6 Van der Waals
EB1001 F270 6.55x55 TM6 hydrophobic
EB1001 Y280 ECL3 hydrophobic
EB1001 Y280 ECL3 Van der Waals
EB1001 I285 7.31x30 TM7 hydrophobic
EB1001 I285 7.31x30 TM7 Van der Waals
EB1001 Q286 7.32x31 TM7 polar (hydrogen bond)
EB1001 Q286 7.32x31 TM7 polar (hydrogen bond)
EB1001 Y289 7.35x34 TM7 polar (hydrogen bond)
EB1001 Y289 7.35x34 TM7 polar (hydrogen bond)

Ligands

EB1001

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Residue Diagrams

A N G T V A V L V L A L Y A T A W L A L 1 V N L A L A D L C M A A F N A A F N F V 2 A T M S Y I S V F M A T I P F L N Q F Y 3 T K A V I A G I W L V A L A L A S P Q 4 Y A V F M V A L P L F Y I L A I V V L H Y 5 V L V V L T F A I C W L P Y H L Y F I L 6 I P N Y M T S S M A L W F L A L Y V Q 7
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ICL1 R R M R ICL1ECL1 I W Y F ECL1ICL2 P F Q P R L ICL2ECL2 T V T M D Q G A T K C V V A W P E D ECL2ICL3 Q A H G ICL3ECL3 E D I Y C H ECL3N-term M G T C D I V T E A N I S S G P E S N T T G I T A F S M N-termC-term R C C P W V T P T K E D K L E L T P T T S L S T R V N R C H T K E T L F M A G D T A P S E A T S G E A G R P Q D G S G L W F G Y G L L A P T K T H V E I C-term P S W Q L A L W A T A Y L A L V L V A V T G N A I V I W I I L A H T V T N Y F I V N L A L A D L C M A A F N A A F N F V Y A S H N G R A F C Y F Q N L F P I T A M F V S I Y S M T A I A A D R Y M A I V H S A P S T K A V I A G I W L V A L A L A S P Q C F Y S S G G K T L L L Y H L V V I A L I Y F L P L A V M F V A Y S V I G L T L W R R A V P G H A N L R H L Q A M K K F V K T M V L V V L T F A I C W L P Y H L Y F I L G S F Q K F I Q Q V Y L A L F W L A M S S T M Y N P I I Y C C L N H R F R L F R S G A F
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Residue Table


GPCRdb(A)
GPCRdb(A)
NK2 receptor
TM2
2x57 2.57x57 N86
2x61 2.61x61 N90
2x64 2.64x64 Y93
2x68 2.68x68 N97
TM3
3x33 3.33x33 I114
ECL2
45x51 45.51x51 V182
TM6
6x51 6.51x51 Y266
6x54 6.54x54 Y269
6x55 6.55x55 F270
TM7
7x30 7.31x30 I285
7x31 7.32x31 Q286
7x34 7.35x34 Y289