Structure information

δ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9XF4

SPECIES

Homo sapiens

RESOLUTION

3.050

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

July 8, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
BMS-986187 L97 2.52x52 TM2 hydrophobic
[Leu]enkephalin (Human) K108 2.63x63 TM2 polar (charge-assisted hydrogen bond)
BMS-986187 L119 3.23x23 TM3 hydrophobic
BMS-986187 A123 3.27x27 TM3 hydrophobic
[Leu]enkephalin (Human) L125 3.29x29 TM3 hydrophobic
[Leu]enkephalin (Human) L125 3.29x29 TM3 Van der Waals
[Leu]enkephalin (Human) Y129 3.33x33 TM3 Van der Waals
BMS-986187 Y130 3.34x34 TM3 hydrophobic
[Leu]enkephalin (Human) R192 ECL2 Van der Waals
[Leu]enkephalin (Human) V217 5.42x43 TM5 Van der Waals
[Leu]enkephalin (Human) V217 5.42x43 TM5 hydrophobic
[Leu]enkephalin (Human) I277 6.51x51 TM6 hydrophobic
[Leu]enkephalin (Human) I277 6.51x51 TM6 Van der Waals
[Leu]enkephalin (Human) H278 6.52x52 TM6 Van der Waals
[Leu]enkephalin (Human) V281 6.55x55 TM6 Van der Waals
[Leu]enkephalin (Human) V281 6.55x55 TM6 hydrophobic
[Leu]enkephalin (Human) I304 7.39x38 TM7 hydrophobic
[Leu]enkephalin (Human) I304 7.39x38 TM7 Van der Waals

Ligands

BMS-986187

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[Leu]enkephalin (Human)

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Residue Diagrams

V N G L L G V A C V A S Y L A T I A I A 1 F N L A L A D A L A T S T L P F Q S A K 2 M T L T F I S T F M N Y Y D I S L V A K 3 A K L I N I C I W V L A S G V G V P I M 4 Y C V T I I L I P V V F A F L F V C I K T 5 L V V V G A F V V C W A P I H I F V I V 6 V P N L S S N A Y G L A I C L H L A A 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 V T R P R D G A V V C M L Q F P S ECL2ICL3 R L L S G ICL3ECL3 D I D R R ECL3N-term M E P A P S A G A E L Q P P L F A N A S D A Y P S A C P S A G A N A S G P P N-termC-term P C G R P D P S S F S R A R E A T A R E R V T A C T P S D G P G G G A A A C-term G A R S A S S L A L A I A I T A L Y S A V C A V G L L G N V L V M F G I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S A K Y L M E G E L L C K A V L S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P A K A K L I N I C I W V L A S G V G V P I M V M A P S W Y W D T V T K I C V F L F A F V V P I L I I T V C Y G L M L L R L R S V S K E K D R S L R R I T R M V L V V V G A F V V C W A P I H I F V I V W T L V D P L V V A A L H L C I A L G Y A N S S L N P V L Y A F L D E N F R Q F K R C L C R K
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Residue Table


GPCRdb(A)
GPCRdb(A)
δ receptor
TM2
2x52 2.52x52 L97
2x63 2.63x63 K108
TM3
3x23 3.23x23 L119
3x27 3.27x27 A123
3x29 3.29x29 L125
3x33 3.33x33 Y129
3x34 3.34x34 Y130
TM5
5x43 5.42x43 V217
TM6
6x51 6.51x51 I277
6x52 6.52x52 H278
6x55 6.55x55 V281
TM7
7x38 7.39x38 I304