CHEMBL289683


SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2CC1CC1
InChIKey YQYVFVRQLZMJKJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 271.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.96 8.96 8.96 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.74 9.74 9.74 ChEMBL
δ OPRD Human Opioid A pKi 8.7 8.7 8.7 ChEMBL
κ OPRK Human Opioid A pKi 10.15 10.15 10.15 ChEMBL
μ OPRM Human Opioid A pKi 9.8 9.8 9.8 ChEMBL
μ OPRM Human Opioid A pKi 9.66 9.82 10.0 PDSP Ki database
δ OPRD Human Opioid A pKi 8.7 8.9 9.1 PDSP Ki database
κ OPRK Human Opioid A pKi 10.0 10.07 10.15 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 9.74 9.87 10.0 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.96 9.09 9.22 PDSP Ki database
μ OPRM Rat Opioid A pKi 8.82 8.94 9.05 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database