CHEMBL292521


SMILES CC[C@@H]1CN2CCc3c([nH]c4cccc(O)c34)[C@@H]2C[C@@H]1/C(=C\OC)C(=O)OC
InChIKey IIRZCWUQUBSIPF-XZNUVMSOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 5.93 5.93 5.93 ChEMBL
μ OPRM Mouse Opioid A pKi 6.67 6.67 6.67 ChEMBL
δ OPRD Mouse Opioid A pKi 5.72 5.72 5.72 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.53 5.53 5.53 ChEMBL
δ OPRD Human Opioid A pKi 4.51 4.51 4.51 ChEMBL
μ OPRM Human Opioid A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pEC50 6.07 6.07 6.07 ChEMBL
μ OPRM Mouse Opioid A pEC50 6.37 6.37 6.37 ChEMBL