CHEMBL301559


SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
InChIKey BLYMJBIZMIGWFK-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 247.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Bovine Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Rat Dopamine A pKd 5.96 6.22 6.52 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.49 5.49 5.49 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 4.07 4.07 4.07 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.05 8.76 9.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 7.47 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.3 5.64 6.55 ChEMBL