CHEMBL303855


SMILES C=CCN1CC(C)N(C(c2ccc(C(=O)N(CC)CC)cc2)c2cccc(O)c2)CC1C
InChIKey LBLDMHBSVIVJPM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 435.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 11.0 11.0 11.0 PDSP Ki database
κ OPRK Human Opioid A pKi 7.77 7.77 7.77 PDSP Ki database
μ OPRM Human Opioid A pKi 7.59 7.59 7.59 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 9.04 9.37 9.7 ChEMBL
μ OPRM Rat Opioid A pIC50 7.33 7.33 7.33 ChEMBL