CHEMBL303921


SMILES CCCN(CCCOc1cccc(Cl)c1)C1CCc2ccc3[nH]cc(C=O)c3c2C1
InChIKey KTENZVQFGHICMF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.73 6.73 6.73 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database