CHEMBL1161416


SMILES Cc1cc(O)cc(C)c1C[C@H](N)[C@@H](O)C/C=C/[C@@H](O)[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey MWAQTMFPZSUQRQ-LSANMVLPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 14
Molecular weight (Da) 559.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.68 7.68 7.68 ChEMBL
δ OPRD Human Opioid A pKi 7.44 7.44 7.44 ChEMBL
μ OPRM Human Opioid A pKi 9.38 9.38 9.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 8.1 8.1 8.1 ChEMBL