CHEMBL308570


SMILES Cc1c(Nc2ncc[nH]2)ccc2c1OCCO2
InChIKey NDFYRGCPDAFQDG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 231.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pKi 7.09 7.09 7.09 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.72 7.72 7.72 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.77 8.77 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pEC50 7.39 7.39 7.39 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 8.18 8.18 8.18 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 8.06 8.06 8.06 ChEMBL