compound 26 [PMID: 16439120]


SMILES N#Cc1cc(OCc2ccnc(c2)C)nc(c1)Cl
InChIKey MWMMUKIHNXXNGW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 259.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 8.0 8.0 8.0 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database