CHEMBL3120696


SMILES Cc1c(OCCCCN2CCC(c3noc4cc(F)ccc34)CC2)ccc2c3c(c(=O)oc12)CCC3
InChIKey MOCKMRLKGXHIFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 490.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.87 7.87 7.87 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 5.74 5.74 5.74 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.9 7.9 7.9 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.11 8.11 8.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database