CHEMBL31217


SMILES CN1CCN(c2cccc3ccc(OCCOc4ccc5[nH]cc(CCN)c5c4)cc23)CC1
InChIKey CCEYDGKRXQRJOJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 444.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.12 9.12 9.12 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.02 9.02 9.02 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.02 9.02 9.02 PDSP Ki database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.12 9.12 9.12 PDSP Ki database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database