CHEMBL3122224


SMILES CCN(CC)C(=O)c1nn(C)c2nc(OCc3ccccn3)ccc12
InChIKey PYGURBRUNSVSMZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 8.31 8.31 8.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 5.23 5.23 5.23 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 8.25 8.25 8.25 ChEMBL