CYPRODIME


SMILES COc1cccc2c1[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(OC)CCC(=O)C3
InChIKey INUCRGMCKDQKNA-CEMLEFRQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.96 7.05 7.21 ChEMBL
μ OPRM Rat Opioid A pKi 4.97 6.47 7.97 ChEMBL
δ OPRD Human Opioid A pKi 6.98 7.1 7.21 ChEMBL
μ OPRM Human Opioid A pKi 7.97 7.97 7.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 5.96 5.96 5.96 ChEMBL
κ OPRK Human Opioid A pEC50 6.93 6.93 6.93 ChEMBL
μ OPRM Human Opioid A pEC50 7.69 7.69 7.69 ChEMBL