CHEMBL325347


SMILES O=C1CC[C@@]2(OCCCc3ccccc3)[C@H]3Cc4cccc(O)c4C2(CCN3CC2CC2)C1
InChIKey IWZLUXJMEHSPFL-OIKXHLBWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 445.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 5.23 5.23 5.23 ChEMBL
μ OPRM Rat Opioid A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.1 8.1 8.1 ChEMBL
κ OPRK Human Opioid A pEC50 8.35 8.35 8.35 ChEMBL
μ OPRM Human Opioid A pEC50 8.46 8.46 8.46 ChEMBL