CHEMBL325772


SMILES COc1c(C(=O)N[C@@H]2CCN(Cc3ccccc3)C2)cc(I)c2ccccc12
InChIKey MNUMQOWSJLDQOS-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 486.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.21 5.37 5.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.48 8.7 8.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.47 7.47 7.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.72 7.18 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database