CHEMBL330108


SMILES O=C1Cc2c(ccc(Cl)c2N2CCN(Cc3ccccc3)CC2)N1
InChIKey PIPVZEXRFVHTJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 341.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.27 6.68 7.26 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.27 6.27 6.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database