CHEMBL3325714


SMILES Cc1nn(-c2ccc(Br)cc2Br)c2c1C(=O)CC(C)(C)C2
InChIKey IXQVTUGHVSDDBK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 410.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 6.33 6.33 6.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 5.77 5.77 5.77 ChEMBL
κ OPRK Human Opioid A pIC50 6.39 6.39 6.39 ChEMBL
μ OPRM Human Opioid A pEC50 5.26 6.32 7.39 ChEMBL
μ OPRM Human Opioid A pIC50 6.14 6.14 6.14 ChEMBL